Excess mortality after hip fracture in elderly persons from Europe and the USA: the CHANCES project
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F75010330%3A_____%2F17%3A00011695" target="_blank" >RIV/75010330:_____/17:00011695 - isvavai.cz</a>
Result on the web
<a href="http://onlinelibrary.wiley.com/doi/10.1111/joim.12586/abstract;jsessionid=BE72A1637FBF8B4F28B6A44A2457C293.f03t02" target="_blank" >http://onlinelibrary.wiley.com/doi/10.1111/joim.12586/abstract;jsessionid=BE72A1637FBF8B4F28B6A44A2457C293.f03t02</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/joim.12586" target="_blank" >10.1111/joim.12586</a>
Alternative languages
Result language
angličtina
Original language name
Excess mortality after hip fracture in elderly persons from Europe and the USA: the CHANCES project
Original language description
Background Hip fractures are associated with diminished quality of life and survival especially amongst the elderly. Objective All-cause mortality after hip fracture was investigated to assess its magnitude. Methods A total of 122 808 participants from eight cohorts in Europe and the USA were followed up for a mean of 12.6 years, accumulating 4273 incident hip fractures and 27 999 deaths. Incident hip fractures were assessed through telephone interviews/questionnaires or national inpatient/fracture registries, and causes of death were verified with death certificates. Cox proportional hazards models and the time-dependent variable methodology were used to assess the association between hip fracture and mortality and its magnitude at different time intervals after the injury in each cohort. We obtained the effect estimates through a random-effects meta-analysis. Results Hip fracture was positively associated with increased all-cause mortality, the hazard ratio (HR) in the fully adjusted model was 2.12, 95% confidence interval (CI) 1.76-2.57, after adjusting for potential confounders. This association was stronger amongst men [HR: 2.39, 95% CI: 1.72-3.31] than amongst women [HR: 1.92, 95% CI: 1.54-2.39], although this difference was not significant. Mortality was higher during the first year after the hip fracture [HR: 2.78, 95% CI: 2.12-3.64], but it remained elevated without major fluctuations after longer time since hip fracture [HR (95% CI): 1.89 (1.50-2.37) after 1-4 years, 2.15 (1.81-2.55) after 4-8 years, 1.79 (1.57-2.05) after 8 or more years]. Conclusion In this large population-based sample of older persons across eight cohorts, hip fracture was associated with excess short- and long-term all-cause mortality in both sexes.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30304 - Public and environmental health
Result continuities
Project
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Continuities
N - Vyzkumna aktivita podporovana z neverejnych zdroju
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Internal Medicine
ISSN
0954-6820
e-ISSN
1365-2796
Volume of the periodical
281
Issue of the periodical within the volume
3
Country of publishing house
US - UNITED STATES
Number of pages
11
Pages from-to
300-310
UT code for WoS article
000394893800007
EID of the result in the Scopus database
2-s2.0-85012979808