Urinary cadmium and cotinine levels and hair mercury levels in Czech children and their mothers within the framework of the COPHES/DEMOCOPHES projects

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F75010330%3A_____%2F17%3A00011800" target="_blank" >RIV/75010330:_____/17:00011800 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11120/17:43913276

Result on the web

<a href="https://link.springer.com/article/10.1007%2Fs00244-017-0412-y" target="_blank" >https://link.springer.com/article/10.1007%2Fs00244-017-0412-y</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00244-017-0412-y" target="_blank" >10.1007/s00244-017-0412-y</a>

Result language

angličtina

Original language name

Urinary cadmium and cotinine levels and hair mercury levels in Czech children and their mothers within the framework of the COPHES/DEMOCOPHES projects

Original language description

The COPHES/DEMOCOPHES twin project was performed in 2011-2012 in 17 European countries to harmonize all steps of the human biomonitoring survey. Urinary cadmium, cotinine, phthalate metabolites, and hair mercury were measured in children (N = 120, 6-11 years) and their mothers of reproductive age, living in urban or rural areas. Cadmium in mothers' and children's urine was detected at a geometric mean (GM) concentration 0.227 and 0.109 mu g/L, respectively. 95th percentile (P95) was 0.655 and 0.280 mu g/L in mothers and children, respectively. No age-related, education-related, or urban versus rural differences were observed within the frame of each population group. Cadmium urinary level in mothers was about twofold compared with children. Higher levels were obtained in all smoking mothers but not in occasionally smoking or mothers and children exposed to environmental tobacco smoke (ETS). Mercury values in mothers were significantly higher in urban than in rural populations but not in children. GM and P95 for mercury in children's hair were 0.098 and 0.439 mu g/g and in mothers' hair were 0.155 and 0.570 mu g/g. Concentrations for mercury in the Czech samples were lower than European average. Hair mercury increased significantly with consumption of fish or seafood and with number of amalgam tooth fillings (in children). A positive association was found with family educational level. No influence of age was observed. Urinary cadmium and hair mercury levels were lower than health-based guidelines with one exception. High levels of urinary cotinine were found in the 12 smoking mothers (GM approximately 500 mu g/L); lower levels in occasionally smoking mothers, N = 11 (34.5 mu g/L). The mean cotinine levels in nonsmoking mothers who reported daily exposure to ETS was 10.7 mu g/L. A similar mean value (10.8 mu g/L) was obtained in six children who had daily exposure to ETS. In children without exposure to ETS, the mean cotinine level was 1.39 mu g/L urine. Cotinine in the urine of children demonstrates limited protection of the Czech children against exposure to ETS.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30304 - Public and environmental health

Project

<a href="/en/project/7EX11063" target="_blank" >7EX11063: Demonstration of a study to coordinate and perform human biomonitoring on a European scale</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Archives of Environmental Contamination and Toxicology

ISSN

0090-4341

e-ISSN

1432-0703

Volume of the periodical

73

Issue of the periodical within the volume

3

Country of publishing house

US - UNITED STATES

Number of pages

10

Pages from-to

421-430

UT code for WoS article

000410258100007

EID of the result in the Scopus database

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