Staphylococcus aureus bloodstream infections: diverging trends of meticillin-resistant and meticillin-susceptible isolates, EU/EEA, 2005 to 2018
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F75010330%3A_____%2F21%3A00013732" target="_blank" >RIV/75010330:_____/21:00013732 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11120/21:43922630 RIV/00064173:_____/21:N0000163
Result on the web
<a href="https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2021.26.46.2002094" target="_blank" >https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2021.26.46.2002094</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2807/1560-7917.ES.2021.26.46.2002094" target="_blank" >10.2807/1560-7917.ES.2021.26.46.2002094</a>
Alternative languages
Result language
angličtina
Original language name
Staphylococcus aureus bloodstream infections: diverging trends of meticillin-resistant and meticillin-susceptible isolates, EU/EEA, 2005 to 2018
Original language description
Background: Invasive infections caused by Staphylococcus aureus have high clinical and epide-miological relevance. It is therefore important to moni-tor the S. aureus trends using suitable methods. Aim: The study aimed to describe the trends of blood-stream infections (BSI) caused by meticillin-resistant S. aureus (MRSA) and meticillin-susceptible S. aureus (MSSA) in the European Union (EU) and the European Economic Area (EEA). Methods: Annual data on S. aureus BSI from 2005 to 2018 were obtained from the European Antimicrobial Resistance Surveillance Network (EARS-Net). Trends of BSI were assessed at the EU/EEA level by adjusting for blood culture set rate (number of blood culture sets per 1,000 days of hospitalisation) and stratification by patient charac-teristics.Results: Considering a fixed cohort of labo-ratories consistently reporting data over the entire study period, MRSA percentages among S. aureus BSI decreased from 30.2% in 2005 to 16.3% in 2018. Concurrently, the total number of BSI caused by S. aureus increased by 57%, MSSA BSI increased by 84% and MRSA BSI decreased by 31%. All these trends were statistically significant (p < 0.001). Conclusions: The results indicate an increasing health burden of MSSA BSI in the EU/EEA despite a significant decrease in the MRSA percentage. These findings highlight the importance of monitoring antimicrobial resistance trends by assessing not only resistance percentages but also the incidence of infections. Further research is needed on the factors associated with the observed trends and on their attributable risk.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30303 - Infectious Diseases
Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Euro Surveillance
ISSN
1025-496X
e-ISSN
1560-7917
Volume of the periodical
26
Issue of the periodical within the volume
46
Country of publishing house
SE - SWEDEN
Number of pages
9
Pages from-to
2002094
UT code for WoS article
000721002800002
EID of the result in the Scopus database
2-s2.0-85121231527