Time patterns in internal human exposure data to bisphenols, phthalates, DINCH, organophosphate flame retardants, cadmium and polyaromatic hydrocarbons in Europe

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F75010330%3A_____%2F23%3A00014389" target="_blank" >RIV/75010330:_____/23:00014389 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14310/23:00132401

Result on the web

<a href="https://www.mdpi.com/2305-6304/11/10/819" target="_blank" >https://www.mdpi.com/2305-6304/11/10/819</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/toxics11100819" target="_blank" >10.3390/toxics11100819</a>

Result language

angličtina

Original language name

Time patterns in internal human exposure data to bisphenols, phthalates, DINCH, organophosphate flame retardants, cadmium and polyaromatic hydrocarbons in Europe

Original language description

Human biomonitoring (HBM) data in Europe are often fragmented and collected in different EU countries and sampling periods. Exposure levels for children and adult women in Europe were evaluated over time. For the period 2000-2010, literature and aggregated data were collected in a harmonized way across studies. Between 2011-2012, biobanked samples from the DEMOCOPHES project were used. For 2014-2021, HBM data were generated within the HBM4EU Aligned Studies. Time patterns on internal exposure were evaluated visually and statistically using the 50th and 90th percentiles (P50/P90) for phthalates/DINCH and organophosphorus flame retardants (OPFRs) in children (5-12 years), and cadmium, bisphenols and polycyclic aromatic hydrocarbons (PAHs) in women (24-52 years). Restricted phthalate metabolites show decreasing patterns for children. Phthalate substitute, DINCH, shows a non-significant increasing pattern. For OPFRs, no trends were statistically significant. For women, BPA shows a clear decreasing pattern, while substitutes BPF and BPS show an increasing pattern coinciding with the BPA restrictions introduced. No clear patterns are observed for PAHs or cadmium. Although the causal relations were not studied as such, exposure levels to chemicals restricted at EU level visually decreased, while the levels for some of their substitutes increased. The results support policy efficacy monitoring and the policy-supportive role played by HBM.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30304 - Public and environmental health

Project

—

Continuities

R - Projekt Ramcoveho programu EK

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Toxics

ISSN

2305-6304

e-ISSN

2305-6304

Volume of the periodical

11

Issue of the periodical within the volume

10

Country of publishing house

CH - SWITZERLAND

Number of pages

23

Pages from-to

819

UT code for WoS article

001095006000001

EID of the result in the Scopus database

2-s2.0-85175447527