Predictors of severity of influenza-related hospitalizations: results from the Global Influenza Hospital Surveillance Network (GIHSN)
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F75010330%3A_____%2F23%3A00014390" target="_blank" >RIV/75010330:_____/23:00014390 - isvavai.cz</a>
Result on the web
<a href="https://academic.oup.com/jid/advance-article/doi/10.1093/infdis/jiad303/7234909" target="_blank" >https://academic.oup.com/jid/advance-article/doi/10.1093/infdis/jiad303/7234909</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1093/infdis/jiad303" target="_blank" >10.1093/infdis/jiad303</a>
Alternative languages
Result language
angličtina
Original language name
Predictors of severity of influenza-related hospitalizations: results from the Global Influenza Hospital Surveillance Network (GIHSN)
Original language description
The Global Influenza Hospital Surveillance Network (GIHSN) has since 2012 provided patient-level data on severe influenza-like-illnesses from >100 participating clinical sites worldwide based on a core protocol and consistent case definitions. Methods. We used multivariable logistic regression to assess the risk of intensive care unit admission, mechanical ventilation, and in-hospital death among hospitalized patients with influenza and explored the role of patient-level covariates and country income level. Results. The data set included 73 121 patients hospitalized with respiratory illness in 22 countries, including 15 660 with laboratory-confirmed influenza. After adjusting for patient-level covariates we found a 7-fold increase in the risk of influenzarelated intensive care unit admission in lower middle-income countries (LMICs), compared with high-income countries (P =.01). The risk of mechanical ventilation and in-hospital death also increased by 4-fold in LMICs, though these differences were not statistically significant. We also find that influenza mortality increased significantly with older age and number of comorbid conditions. Across all severity outcomes studied and after controlling for patient characteristics, infection with influenza A/H1N1pdm09 was more severe than with A/H3N2. Conclusions. Our study provides new information on influenza severity in underresourced populations, particularly those in LMICs.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30303 - Infectious Diseases
Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Infectious Diseases
ISSN
0022-1899
e-ISSN
1537-6613
Volume of the periodical
229
Issue of the periodical within the volume
4
Country of publishing house
US - UNITED STATES
Number of pages
11
Pages from-to
999-1009
UT code for WoS article
001064090900001
EID of the result in the Scopus database
2-s2.0-85185448470