Prevalence of Borrelia burgdorferi sensu lato infection in the Czech Republic
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F75010330%3A_____%2F25%3A00015044" target="_blank" >RIV/75010330:_____/25:00015044 - isvavai.cz</a>
Alternative codes found
RIV/60162694:G44__/26:00564143
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S1438422124000481?pes=vor&utm_source=clarivate&getft_integrator=clarivate" target="_blank" >https://www.sciencedirect.com/science/article/pii/S1438422124000481?pes=vor&utm_source=clarivate&getft_integrator=clarivate</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.ijmm.2024.151644" target="_blank" >10.1016/j.ijmm.2024.151644</a>
Alternative languages
Result language
angličtina
Original language name
Prevalence of Borrelia burgdorferi sensu lato infection in the Czech Republic
Original language description
Introduction: Lyme borreliosis (LB), an infection caused by Borrelia burgdorferi sensu lato (Bbsl), is the most common tick-borne disease in Europe. To further characterize the LB burden in the Czech Republic, we conducted a seroprevalence study and estimated the incidence of symptomatic Bbsl infections. Methods: Anti-Bbsl IgM and IgG antibodies were detected in sera collected from the adult population in 2011-2012 by enzyme-linked immunosorbent assay and immunoblot tests at the National Reference Laboratory. The incidence of symptomatic Bbsl infections was estimated from the seroprevalence results and the symptomatic proportion and duration of persistence of anti-Bbsl IgG antibodies in Bbsl-infected individuals. Surveillance under-detection of symptomatic Bbsl infections was estimated by comparing surveillance-reported and seroprevalence-based incidence. Results: Samples from 1996 adults were tested; the median age (range) was 45 (18-87) years; 1037 (52.0 %) were female. The prevalence (with 95 % confidence interval) of anti-Bbsl IgG, and IgM and/or IgG (IgM/IgG) antibodies was 6.3 % (5.3-7.5 %), and 9.5 % (8.3-10.9 %), respectively. The IgM/IgG prevalence was 7.8 % (6.5-9.2 %) in Bohemia and 15.3 % (12.2-19.0 %) in Moravia. There were an estimated 30,563 (26,550-34,962) symptomatic incident Bbsl infections in adults in the Czech Republic in 2012, for an incidence of 352.2 (306.0-402.9) symptomatic Bbsl infections per 100,000 adults per year. There were an estimated 11 (10-13) symptomatic Bbsl infections for each surveillance-reported LB case in the Czech Republic in 2012. Conclusions: There is high incidence of symptomatic Bbsl infections in the Czech Republic, particularly in Moravia. Interventions are needed to address the substantial burden of LB in the Czech Republic.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30303 - Infectious Diseases
Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
International Journal of Medical Microbiology
ISSN
1438-4221
e-ISSN
1618-0607
Volume of the periodical
318
Issue of the periodical within the volume
March
Country of publishing house
DE - GERMANY
Number of pages
6
Pages from-to
151644
UT code for WoS article
001407740900001
EID of the result in the Scopus database
2-s2.0-85214012016