Optimizing cyanobacterial product synthesis: Meeting the challenges
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F86652079%3A_____%2F16%3A00464727" target="_blank" >RIV/86652079:_____/16:00464727 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1080/21655979.2016.1207017" target="_blank" >http://dx.doi.org/10.1080/21655979.2016.1207017</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1080/21655979.2016.1207017" target="_blank" >10.1080/21655979.2016.1207017</a>
Alternative languages
Result language
angličtina
Original language name
Optimizing cyanobacterial product synthesis: Meeting the challenges
Original language description
The synthesis of renewable bioproducts using photosynthetic microorganisms holds great promise. Sustainable industrial applications, however, are still scarce and the true limits of phototrophic production remain unknown. One of the limitations of further progress is our insufficient understanding of the quantitative changes in photoautotrophic metabolism that occur during growth in dynamic environments. We argue that a proper evaluation of the intra- and extracellular factors that limit phototrophic production requires the use of highly-controlled cultivation in photobioreactors, coupled to real-time analysis of production parameters and their evaluation by predictive computational models. In this addendum, we discuss the importance and challenges of systems biology approaches for the optimization of renewable biofuels production. As a case study, we present the utilization of a state-of-the-art experimental setup together with a stoichiometric computational model of cyanobacterial metabolism for quantitative evaluation of ethylene production by a recombinant cyanobacterium Synechocystis sp. PCC 6803.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Bioengineered
ISSN
2165-5979
e-ISSN
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Volume of the periodical
7
Issue of the periodical within the volume
6
Country of publishing house
US - UNITED STATES
Number of pages
7
Pages from-to
490-496
UT code for WoS article
000387292200016
EID of the result in the Scopus database
2-s2.0-84982262073