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The role of tyrosine 90 in regulation of Src kinase activity and its interaction with signaling partners
Analysis of the role of tyrosine 90 in regulation of Src kinase activity and in its interaction with signaling partners...
EB - Genetika a molekulární biologie
- 2008 •
- D
Rok uplatnění
D - Stať ve sborníku
p47phox molecular activation for assembly of the neutrophil NADPH oxidase complex
Paper describes mechanism of molecular activation of p47phox, one part of the NADPH oxidase complex. P47phox is a modular multidomain protein that is known to undergo process of activation via phosphorylation. Due to the modular nature and its size i...
CE - Biochemie
- 2010 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Elucidation of protein interactions necessary for the maintenance of the BCR-ABL signaling complex
disordered region of BCR-ABL, that SHC1 requires pleckstrin homology, src homology and tyrosine kinase domains of BCR-ABL for binding, and that BCR-ABL sequence motif located complex members, i.e., GRB2, SOS1, and...
Developmental biology
- 2020 •
- Jimp •
- Link
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Specific phosphorylation of microtubule-associated protein 2c by extracellular signal–regulated kinase reduces interactions at its Pro-rich regions
Grb2, Src homology domain 3 of tyrosine kinases Fyn and Abl, and ERK2 itself. We by a model cyclin-dependent kinase CDK2 and with phosphorylation of the MAP2c homolog Tau......
Biochemistry and molecular biology
- 2022 •
- Jimp •
- Link
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
The regulatory region of Prague C v-Src inhibits the activity of the Schmidt-Ruppin A v-Src kinase domain-pY527 interaction.
Low activity of v-src of Prague C strain of Raus sarcoma virus kinase is caused by mutations in SH3 domain rather than in kinase domain itself......
EB - Genetika a molekulární biologie
- 2002 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
The 3´ untranslated region of the chicken c-src protooncogene modulates gene expression
The chicken c-src 3´UTR effects on gene expression have been explored. The c-src 3´UTR decreased the in vivo tumorigenic potential of the src-activated mutants in chickens. This corresponds with the findin...
EB - Genetika a molekulární biologie
- 2003 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
The SH3 domain of Src can downregulate its kinase activity in the absence of the SH2 domain-pY527 interaction.
Low kinase activity of Prague v-src depends on primery structure of SH3 domain...
EB - Genetika a molekulární biologie
- 2002 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
SUG-1 Plays Proteolytic and Non-proteolytic Roles in the Control of Retinoic Acid Target Genes via Its Interaction with SRC-3
Nuclear retinoic acid receptor alpha (RAR alpha) activates gene expression through dynamic interactions with coregulatory protein complexes, the assembly of which is directed by the ligand and the AF-2 domain of RAR alpha. Then RAR alpha and...
FB - Endokrinologie, diabetologie, metabolismus, výživa
- 2009 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CAS directly interacts with vinculin to control mechanosensing and focal adhesion dynamics
. This interaction is mediated by the CAS SRC homology 3 domain and a proline-rich sequencein...
EB - Genetika a molekulární biologie
- 2014 •
- Jx •
- Link
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
Inhibition of PHLDA3 expression in human superoxide dismutase 1-mutant amyotrophic lateral sclerosis astrocytes protects against neurotoxicity
Pleckstrin homology-like domain family A-member 3 (PHLDA3) has recently been of pleckstrin homology-like domain family A-member 3 signalling was shown to vary across homology-like dom...
Neurosciences (including psychophysiology)
- 2024 •
- Jimp •
- Link
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
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