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208 850 (0,169s) •

Result

Expression of multidrug resistance protein 1and multidrug resistance-associated protein 1in peripheral blood lymphocytes amongst children and young adults

Multidrug resistance protein 1 (MDR1, ABCB1 or P-glycoprotein) and multidrug resistance-associated protein 1 (MRP1, ABCC1 or LT C4 transporter) are active membrane-a...

EC - Imunologie

  • 2013
    • •
  • Jx
    • •
  • Link
Result

Defying Multidrug Resistance! Modulation of Related Transporters by Flavonoids and Flavonolignans

multidrug resistance by inhibiting Adenosine triphosphate Binding Cassette (ABC)-transporters (human P-glycoprotein, multidrug resistance-associated protein MRP-1, breast cancer resi...

Biochemistry and molecular biology

  • 2020
    • •
  • Jimp
    • •
  • Link
Result

Importance of ABCC1 for cancer therapy and prognosis

resistance associated protein 1 (MRP1) encoded by ABCC1 geneMultidrug resistance presents one of the most important causes of cancer treatment failure. Numerous in vitro and in vivo data have mad...

FD - Onkologie a hematologie

  • 2014
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  • Jx
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  • Link
Result

Multidrug resistance-associated ABC transporters ? too much of one thing, good for nothing

results in multidrug resistance (MDR) which leads to unsuccessful chemotherapy. The most important MDR-associated members of ABC superfamily are ABC B1/P-glycoprotein/MDR1, ABC C1/multidrug resistance

ED - Fyziologie

  • 2012
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  • Jx
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  • Link
Result

Zonation of multidrug resistance-associated protein 2 in rat liver after induction with dexamethasone

The study is aimed to evaluate the hepatic zonation of multidrug resistance-associated protein 2 (mrp2), an important drug transporter, and its potential changes during the induction of its expression by known indu...

FR - Farmakologie a lékárnická chemie

  • 2008
    • •
  • Jx
Result

Role of ABCB1, ABCG2, ABCC2 and ABCC5 transporters in placental passage of zidovudine

We aimed to contribute to current knowledge on AZT transplacental transport and to evaluate potential involvement of the main human drug efflux ATP-binding cassette (ABC) transporters, p-glycoprotein (ABCB1), breast cancer resistance pro...

FR - Farmakologie a lékárnická chemie

  • 2016
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  • Jx
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  • Link
Result

The role of ABC transporters associated with multidrug resistance in stem cells

/P-glycoprotein/MDR1, ABCC1/multidrug resistance-associated protein 1 (MRP1), and ABCG2/BCRP (Breast cancer resistance protein);. However, substrates of ABC-t/MDR. These transporters are ...

ED - Fyziologie

  • 2013
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  • O
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  • Link
Result

In vitro chemoresistance profile and expression/function of MDR associated proteins in resistant cell lines derived from CCRF-CEM, K562, A549 and MDA MB 231 parental cells

Although cellular experiments have elucidated a number of active principles in the study of the multidrug resistance ( MDR ) phenomena, most of the drug resistant tumor cells were derived from different parenteral cell line...

FJ - Chirurgie včetně transplantologie

  • 2002
    • •
  • Jx
Result

Thiazolidinediones Regulate the Level of ABC Transporters Expression on Lung Cancer Cells

of agonists on transcription of following ABC transporters was investigated: multidrug resistance protein 1 (MDR1), multidrug resistance-associated protein 1 (MRP1), an...

FD - Onkologie a hematologie

  • 2015
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  • Jx
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  • Link
Result

Mechanisms of multidrug resistance and their clinical implications. II. Atypical MDR

A summary is given of atypical multidrug resistance due to 3 different proteins...

FD - Onkologie a hematologie

  • 2000
    • •
  • Jx
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