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Absence of Toll-Like Receptor 4 Signaling Results in Delayed Yersinia enterocolitica YopP-Induced Cell Death of Dendritic Cells
Yersinia outer protein P (YopP) accounts for the induction of cell death in murine dendritic cells (DC). In an initial period (< 4h) Toll-like receptor 4 (TLR4) signaling is required for Yersinia enterocolitica YopP-induced DC death...
EC - Imunologie
- 2007 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Catalytically active Yersinia outer protein P induces cleavage of RIP and caspase-8 at the level of the DISC independently of death receptors in dendritic cells
Yersinia outer protein P (YopP) of Yersinia enterocolitica induces apoptotic and necrosis-like cell death in dendritic cells (DC). YopP induced the cleavage of pro-caspase 8 and c-FLIPL degradation independently of tumor necrosis fa...
EC - Imunologie
- 2007 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Yersinia enterocolitica YopP inhibits MAP kinase-mediated antigen uptake in dendritic cells
Yersinia enterocolitica inhibits the ability of dendritic cells (DC) to trigger T cell activation. Here, we investigated if these bacteria might interfere with antigen prezentation in DCs. We found that Yersinia outer protein P (YopP) of Y. ...
EC - Imunologie
- 2007 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
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