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Electrophile-promoted addition of hydroxymethylphosphonate to 4',5'-didehydronucleosides: a way to novel isosteric analogues of 5'-nucleotides
Electrophile-promoted addition of dialkyl-hydroxymethylphosphonate to 4',5'-didehydronucleosides provided 4'-dialkylphosphonomethoxy derivatives of 2',5'-dideoxynucleosides, novel analogues of 2'-deoxynucleoside 5'-monophos...
CC - Organická chemie
- 2007 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Study of the styrene derivatives behaviour upon electrophilic additions - analysis of susbstitution effects on the reaction mechanism
Series of alpha-alkylsyrenes were prepared, absorbance changes were measured in concentrated solutions of sulphuric acid. The mechanism of acid catalysed hydration of the prepared styrene derivatives was proposed based on above mentioned spectrophoto...
CF - Fyzikální chemie a teoretická chemie
- 2003 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Direct Interaction between N-Acetylcysteine and Cytotoxic Electrophile-An Overlooked In Vitro Mechanism of Protection
n laboratory experiments, many electrophilic cytotoxic agents induce cell death ROS, and is a very weak scavenger of H2O2. In addition, NAC is used, the possibility that NAC as a nucleophile can directly interact with cytotoxic ...
Biochemistry and molecular biology
- 2022 •
- Jimp •
- Link
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Electrophilic Nitro-Fatty Acids: Nitric Oxide and Nitrite-Derived Metabolic and Inflammatory Signaling Mediators
. In addition to its role in activating guanylate cyclase via heme-iron coordination, unsaturated fatty acid nitroalkene derivatives (nitro-fatty acids), is electrophilic and induces PTMs by reversible Michael addition of p...
Cell biology
- 2017 •
- C •
- Link
Rok uplatnění
C - Kapitola v odborné knize
Výsledek na webu
Electrophilic substitution of 2-substituted vinyltin compounds
Electrophilic substitution of vinyltin compounds was studied.
CA - Anorganická chemie
- 2002 •
- D
Rok uplatnění
D - Stať ve sborníku
Cysteamine assay for the evaluation of bioactive electrophiles
of electrophilic compounds towards primary amine and thiol groups in an aqueous environment. This technique is useful for studying the reaction kinetics of electrophiles with thiol (SH to evaluate the reactivity of three electr...
Biochemistry and molecular biology
- 2021 •
- Jimp •
- Link
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Method of direct mono-N-substitution of piperazine
conditions of Michael addition with an electrophilic reagent, preferably in molar ratio piperazine-1-cation to the electrophilic reagent in the range of 1:1 to 1:1,4....
CC - Organická chemie
- 2015 •
- P
Rok uplatnění
P - Patent
2,6-Dihalopurines: Preparation of Magnesiated Purines and their Reaction with Electrophiles.
2,6-Dihalopurines: Preparation of Magnesiated Purines and their Reaction with Electrophiles.
CC - Organická chemie
- 2005 •
- O
Rok uplatnění
O - Ostatní výsledky
Electrophilic polyfluoroalkylating agents based on sulfonate esters
Electrophilic polyfluoroalkylating agents based on sulfonate esters...
CC - Organická chemie
- 2008 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Preparation of fluorohalomethylmagnesium halides using highly active magnesium metal and their reactions.
nucleophilic substitution with silyl halides or nucleophilic addition with aldehydes, benzaldehyde, butyraldehyde or acetophenone as electrophiles, other fluoroorganomagnesium stability and thus the corresponding yields of reaction...
CC - Organická chemie
- 2005 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
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