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Efficient gene targeting of the Rosa26 locus in mouse zygotes using TALE nucleases
TALENs exhibit high targeting efficiency superior to that of zinc-finger nucleases targeting ofthe mouse Rosa26 locus by transcription activator-like effector nucleases......
EB - Genetika a molekulární biologie
- 2014 •
- Jx •
- Link
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
Targeted mutagenesis in the silkworm Bombyx mori using zinc finger nuclease mRNA injection
The absence of a general gene-targeting system for systematic reverse genetic studies has been a significant limitation in silkworm research. The authors performed direct zinc finger nuclease mRNA injection to /B. mori/ emb...
EB - Genetika a molekulární biologie
- 2010 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Genome Editing with Engineered Nucleases in Economically Important Animals and Plants: State of the Art in the Research Pipeline
in the development of breeding techniques. Genome editing using site-directed nucleases - including meganucleases, zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), a...
GM technology (crops and livestock), livestock cloning, marker assisted selection, diagnostics (DNA chips and biosensing devices for the early/accurate detection of diseases) biomass feedstock production technologies, biopharming
- 2017 •
- Jimp •
- Link
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
CCR5 targeted cell therapy for hiv and prevention of viral escape
tested clinically. These techniques include zinc finger nucleases (ZFN), clustered regularly interspaced palindromic repeats/CRISPR-associated protein 9 nuclease (CRISPR/Cas9), transcription activator-like effecto...
FD - Onkologie a hematologie
- 2015 •
- Jx •
- Link
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
Variations in the enzymatic activity of S1-type nucleases results from differences in their active site structures
is the range of non-zinc-dependent S1-like nucleases and what is the molecular basis of their activities. Methods: S1-like nucleases chosen for analysis were achieved through heterologous expression in appropriate eukaryot...
Biochemistry and molecular biology
- 2023 •
- Jimp •
- Link
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Biochemical properties of three plant nucleases with anticancer potential
nucleases exhibit zinc-dependence and a strong stimulatory effect of Zn2+ for dsDNA homologous, plant bifunctional nucleases from tomato (R-TBN1), hop (R-HBN1) and Arabis brassica (R-ABN1) were determined. These nuclea...
EB - Genetika a molekulární biologie
- 2011 •
- Jx •
- Link
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
Mining Frequent Spatial Docking Patterns in Zinc Finger DNA Complexes
We use techniques of logic based relational machine learning to automatically detect spatial patterns common to 21 previously described examples of zinc finger DNA complexes. We demonstrate that such patterns can be found and thus t...
JC - Počítačový hardware a software
- 2010 •
- D
Rok uplatnění
D - Stať ve sborníku
High-frequency, precise modification of the tomato genome
Background: The use of homologous recombination to precisely modify plant genomes has been challenging, due to the lack of efficient methods for delivering DNA repair templates to plant cells. Even with the advent of sequence-specific nucleases
BO - Biofyzika
- 2015 •
- Jx •
- Link
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
Breeding using genome editing: opportunity or threat?
in the development of breeding techniques. Genome editing using site-directed nucleases - including meganucleases, zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), a...
GM technology (crops and livestock), livestock cloning, marker assisted selection, diagnostics (DNA chips and biosensing devices for the early/accurate detection of diseases) biomass feedstock production technologies, biopharming
- 2019 •
- O
Rok uplatnění
O - Ostatní výsledky
Purification of proteins containing zinc finger domains using immobilized metal ion affinity chromatography
of using these approaches, we took an advantage of natural interaction of zinc finger affinities to the immobilized metal ions, despite that both contain the same type of zinc finger motif (i.e., CCHC). While ...
EE - Mikrobiologie, virologie
- 2011 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
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