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50 515 (0,134s)

Result

Invega-paliperidone ER tablets with extended relesase

Paliperidone tablets with extended release is a new antipsychotic drug is an active metabolite of risperidone. The OROS (osmotic controlled-release oral delivery system) technology provides extended re...

FL - Psychiatrie, sexuologie

  • 2008
  • Jx
Result

Formulation design space analysis for drug release from swelling polymer tablets

parameters which affect drug release, namely the drug distribution, maximum swelling heterogeneity study showed that burst release (i.e. dose-dumping) increased as drug loading but the time taken for 99% ...

CI - Průmyslová chemie a chemické inženýrství

  • 2013
  • Jx
  • Link
Result

3D-Printed Coating of Extended-Release Matrix Tablets: Effective Tool for Prevention of Alcohol-Induced Dose Dumping Effect

Tablets used for extended drug release commonly contain large amounts of drugs. The corresponding drug release mechanism thus has to be well-known and invariable under numerous conditions in order...

Pharmacology and pharmacy

  • 2021
  • Jimp
  • Link
Result

The Effect of Acid pH Modifiers on the Release Characteristics of Weakly Basic Drug from Hydrophlilic-Lipophilic Matrices

The solubility of weakly basic drugs within passage though GI tract leads to pH-dependent or even incomplete release of these drugs from extended release formulations and consequently to lower drug

FR - Farmakologie a lékárnická chemie

  • 2013
  • Jx
  • Link
Result

Extended release OROS hydromorphone

with chronic pain management. A novel solution to this problem is slow release OROS times as morphine. The OROS (oral osmotic) drug delivery system controlling the active ingredient release from the tablet, with water cros...

FR - Farmakologie a lékárnická chemie

  • 2007
  • Jx
Result

Influence of pH Modulation on Dynamic Behavior of Gel Layer and Release of Weakly Basic Drug from HPMC/Wax Matrices, Controlled by Acidic Modifiers Evaluated by Multivariate Data Analysis

The solubility of weakly basic drugs in passage through gastrointestinal tract leads to their pH-dependent release from extended release formulations and to lower influence on the release of weakly basic <...

Pharmacology and pharmacy

  • 2017
  • Jimp
  • Link
Result

Shifting from sustained to delayed drug delivery systems: Encapsulated mesoporous silica-chitosan grafted polylactic acid-based composite approach

in the systems for extended and short drug release. Herein, mesoporous silica nanoparticles, which were completed after 12 h and 24 h, respectively. The drug release profiles in the drug rele...

Composites (including laminates, reinforced plastics, cermets, combined natural and synthetic fibre fabrics; filled composites)

  • 2024
  • Jimp
  • Link
Result

Biocompatible material for controlled drug release and transport into the cornea

A drug carrier made of a biocompatible material for controlled drugs release into the cornea of the eye was created, achieving a prolonged 1st order release profile for up to 72 hours. The drug carrier is ...

Ophthalmology

  • 2022
  • Gfunk
Result

Antibacterial porous systems based on polylactide loaded with amikacin

extended release of the drug (amikacin, over 60 days), carried out in accordance composition, and thermogravimetric properties of the released drug. for the controlled release of amikacin. The ma...

Polymer science

  • 2022
  • Jimp
  • Link
Result

Fine tuning of the pH-dependent drug release rate from polyHPMA-ellipticinium conjugates

of the hydrazone bond-containing spacer to find structure?drug release rate relationships. The conjugate selected for further studies shows negligible drug release in apH 7.4 buffer but released 50% of th...

FD - Onkologie a hematologie

  • 2013
  • Jx
  • Link
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