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361 398 (0,467s) •

Result

Genome-wide association study identifies HLA 8.1 ancestral haplotype alleles as major genetic risk factors for myositis phenotypes

Genome-wide association study (GWAS) of the major myositis phenotypes, including those with anti-Jo-1 antibodies was conducted in 1710 patients. Single-nucleotide polymorphisms showing strong associati...

FE - Ostatní obory vnitřního lékařství

  • 2015
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Result

Genome-Wide Association Study for Body Conformation Traits and Fitness in Czech Holsteins

The aim of this study was a genome-wide association study (GWAS for each genotype. Four significant SNPs associated with total score (linear composite identified. The results of our s...

Husbandry

  • 2022
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  • Jimp
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Result

Generating simulated testing data for gennome-wide association studies

genome-wide association studies (GWAS). In GWAS we search for relationships between variations and the phenotype in the entire genomes. Detection of associations betweenRecently...

IN - Informatika

  • 2013
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Result

Genetická determinace věku diagnózy diabetes mellitus 2. typu? Revidovaná koncepce "střádavého genotypu" - editorial

Uplynulých několik málo let přineslo díky výsledkům celogenomových asociačních studií (angl. genome-wide association study, GWAS) poměrně radikální změnu v chápání etiopatogeneze nejběžnějšího typu diabete...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2011
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  • Jx
Result

A Genome-Wide Association Study of Upper Aerodigestive Tract Cancers Conducted within the INHANCE Consortium

Genome-wide association studies (GWAS) have been successful in identifying. We conducted a GWAS to identify common genetic variation involved in susceptibility to upperaero-digestive tract (UADT) ...

FM - Hygiena

  • 2011
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Result

Genome-Wide Analyses Characterize Shared Heritability Among Cancers and Identify Novel Cancer Susceptibility Regions

cancers is not fully known. In this study, we leverage results from twelve cancer genome-wide association studies (GWAS) to quantify pair-wise genome-wide genetic-wide ...

Biological sciences

  • 2023
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  • Jimp
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Result

Investigation of common, low-frequency and rare genome-wide variation in anorexia nervosa

, only one genome-wide significant locus associated with AN has been identified. We performed an exome-chip based genome-wide association studies (GWAS) in 2158 cases from varian...

Psychiatry

  • 2018
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  • Jimp
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Result

A genome-wide association meta-analysis of all-cause and vascular dementia

. Yet, most genome-wide association studies (GWAS) focus on AD. METHODS: We conducted a GWAS of all-cause dementia (ACD) and examined the genetic overlap with VaD-wide association

Neurosciences (including psychophysiology)

  • 2024
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  • Jimp
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Result

Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder

by severe oscillations of mood and behaviour. Genome-wide association studies (GWAS controls, the largest GWAS of BD to date. In this study, to increase power we used for markers on the ...

FL - Psychiatrie, sexuologie

  • 2016
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Result

Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness

Genome-wide association studies (GWAS) of schizophrenia have yielded more than association with either family history subgroup. Comparison of genome-wide polygenic risk is as...

EB - Genetika a molekulární biologie

  • 2016
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