Optimisation of Treatment and Management of Schizophrenia in Europe
Public support
Provider
Ministry of Education, Youth and Sports
Programme
—
Call for proposals
FP7-Health-2009-two-stage
Main participants
Univerzita Karlova / Lékařská fakulta v Hradci Králové
Contest type
RP - Co-financing of EC programme
Contract ID
13595/2011
Alternative language
Project name in Czech
Optimisation of Treatment and Management of Schizophrenia in Europe
Annotation in Czech
Optimise will focus on two goals: optimising current treatments of Schizophrenia and explore novel therapeutic options for schizophrenia. The project intends to both address basic, but so far unanswered, questions in the treatment of schizophrenia and develop new and experimental interventions. It is expected that the project will lead to evidence that is directly applicable to treatment guidelines, will explore the development of novel treatments and will identify potential mechanisms for new drug development. To achieve these goals we have assembled a European team of experts that is second to none in the world. Together we will pursue the following objectives: -To use MRI to optimise treatment outcome and to facilitate prediction of response to treatment; - To provide a rational basis for antipsychotic choices in the treatment of first episode schizophrenia or schizophreniform disorder; - To improve functional outcome and reduce drug discontinuation by means of psychosocial interventions. - To explore the potential of cannabidiol CBD, a modulator of endocannabinoid functioning, as an alternative to D2 based antipsychotics - To validate a new approach to improve cognitive performance in patients with cognitive deficits on the basis of their geneticmake up; - To use theoretically driven neurochemical imaging (PET and MRS) and empirically driven genetic/genomic markers as predictors of response to treatment.
Scientific branches
R&D category
ZV - Basic research
CEP classification - main branch
FL - Psychiatry, sexology
CEP - secondary branch
—
CEP - another secondary branch
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OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)
30215 - Psychiatry<br>30301 - Social biomedical sciences (includes family planning, sexual health, psycho-oncology, political and social effects of biomedical research)
Completed project evaluation
Provider evaluation
U - Uspěl podle zadání (s publikovanými či patentovanými výsledky atd.)
Project results evaluation
Following the condition that the candidate of financial contribution was evaluated and afterwards selected by international provider in accordance with the rules of the program the Ministry of Education, Youth ans Sports does not realize the evaluation of project results. The project is evaluated only after its approval by an international provider.
Solution timeline
Realization period - beginning
Jan 1, 2011
Realization period - end
Dec 31, 2015
Project status
U - Finished project
Latest support payment
Mar 4, 2015
Data delivery to CEP
Confidentiality
C - Předmět řešení projektu podléhá obchodnímu tajemství (§ 504 Občanského zákoníku), ale název projektu, cíle projektu a u ukončeného nebo zastaveného projektu zhodnocení výsledku řešení projektu (údaje P03, P04, P15, P19, P29, PN8) dodané do CEP, jsou upraveny tak, aby byly zveřejnitelné.
Data delivery code
CEP16-MSM-7E-U/01:1
Data delivery date
Oct 6, 2017
Finance
Total approved costs
666 thou. CZK
Public financial support
666 thou. CZK
Other public sources
0 thou. CZK
Non public and foreign sources
0 thou. CZK