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Super resolution (single molecule fluorescent) microscopy for detecting interactions between membrane proteins present at low level

Public support

  • Provider

    Ministry of Education, Youth and Sports

  • Programme

    Promoting the mobility of researchers and workers in the framework of international cooperation in R&D

  • Call for proposals

  • Main participants

    Mikrobiologický ústav AV ČR, v. v. i.

  • Contest type

    M2 - International cooperation

  • Contract ID

    MSMT-12202/2021-32

Alternative language

  • Project name in Czech

    Super-rozlišovací (jednomolekulová fluorescenční) mikroskopie pro detekci interakcí mezi membránovými proteiny přítomných v nízkých úrovních

  • Annotation in Czech

    1) Vyvinout metodu umožňující detekovat interakce membránových proteinů na úrovni jedné molekuly. 2) Analyzovat multimerní stav membránových proteinů S. cerevisiae Trk1/2 a Kch1/2, které se účastní kationtové homeostázy. 3) Analyzovat interakce Trk1/2 a Kch1/2 s jinými proteiny. 4) Monitorovat multimerní stav a detekované interakce za měnících se podmínek, např. různé koncentrace externích jednomocných kationtů

Scientific branches

  • R&D category

    ZV - Basic research

  • OECD FORD - main branch

    10601 - Cell biology

  • OECD FORD - secondary branch

    10606 - Microbiology

  • OECD FORD - another secondary branch

    10602 - Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology

  • CEP - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    EA - Morphology and cytology<br>EE - Microbiology, virology

Completed project evaluation

  • Provider evaluation

    U - Uspěl podle zadání (s publikovanými či patentovanými výsledky atd.)

  • Project results evaluation

    The project was implemented within the framework of the MOBILITY Activity, whose main objective is to establish and deepen contacts with foreign research institutions. Therefore, the partial outputs of the project are not checked by the evaluation committee, but the correctness of the use of the allocated funds and the adequacy of their use are checked.

Solution timeline

  • Realization period - beginning

    Jan 1, 2022

  • Realization period - end

    Apr 19, 2023

  • Project status

    U - Finished project

  • Latest support payment

    Feb 28, 2023

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP24-MSM-8J-U

  • Data delivery date

    Jul 1, 2024

Finance

  • Total approved costs

    144 thou. CZK

  • Public financial support

    144 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    0 thou. CZK