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3 216 (0,099s)

Project

Super resolution (single molecule fluorescent) microscopy for detecting interactions between membrane proteins present at low level (8J22AT012)

proteins Trk1/2 and Kch1/2 which are involved in cation homeostasis. 3) Analyse interactions of Trk1/2 and Kch1/2 with other proteins. 4) Monitor multimeric state1) Develop a method allowing to detect interactions of mem...

Cell biology

  • 2022 - 2023
  • 144 tis. Kč
  • 144 tis. Kč
  • MŠMT
Project

Physiological role of cation/proton antiporters in monovalent cation homeostasis, Ca2+ signalling and intracellular pH regulation (GA17-01953S)

The tight regulation of intracellular ion concentrations is crucial for all cells. Optimal levels of cations are ensured by the coordinated activity of various the properties, regulation and cooperation of various types of cation tr...

EE - Mikrobiologie, virologie

  • 2017 - 2019
  • 5 032 tis. Kč
  • 4 762 tis. Kč
  • GA ČR
Project

Transport of cations and protons across biomembranes - molecular structure and activity mechanism of Na+/H+ antiporter from lower eukaryotes (OC10012)

The aims of the project are 1) to elucidate the molecular structure of a yeast S. cerevisiae plasma-membrane Na+/H+ antiporter transporting alkali metal cations in exchange of protons, 2) to identify amino-acid residues and/or protein

CE - Biochemie

  • 2010 - 2012
  • 3 205 tis. Kč
  • 1 442 tis. Kč
  • MŠMT
Project

Eukaryotic Na+/H+ antiporters – key elements in their structure determining activity, biogenesis and physiological functions (GA21-08985S)

+ antiporters are cation transport systems that participate in ensuring the optimal intracellular level of alkali-metal cations (Na+, K+) and H+ (pH) in the cells of most will provide not only new insights into the principle of ...

Biochemistry and molecular biology

  • 2021 - 2024
  • 5 956 tis. Kč
  • 5 956 tis. Kč
  • GA ČR
Project

Trk1 potassium importers - key transport systems for yeast cell fitness and multiple-stress tolerance (GA20-04420S)

monovalent cations. Its activity influences many physiological parameters, including several Trk proteins from osmotolerant and extremophilic yeasts, compare, the protein’s molecular structure will be studied, together wit...

Microbiology

  • 2020 - 2023
  • 4 993 tis. Kč
  • 4 993 tis. Kč
  • GA ČR
Project

Interactions of metal cations with nucleic acids and their constituents. Ab initio quantum-chemical study (IAA4040903)

The present project will characterize the interactions of metal cations between selected groups of cations and DNA bases, base pairs and other DNA potentials. The differences between various cations (for example zinc vs. ma...

CF - Fyzikální chemie a teoretická chemie

  • 1999 - 2002
  • 2 282 tis. Kč
  • 714 tis. Kč
  • AV ČR
Project

Auto-ionizated Main Group Cations as Catalysts for Ring-Opening Polymerization reactions (GA20-10417S)

group cations of 14 group elements {L1-5MX}+. These cations will be prepared by so with C=N imine functional group. Prepared cations {L1-5MX}+ (M = Ge, Sn) will be tested as the cationic catalysts for ROP reaction...

Polymer science

  • 2020 - 2022
  • 5 325 tis. Kč
  • 5 325 tis. Kč
  • GA ČR
Project

Investigation of Correlation Among Cation Distribution, Particle Size and Physical Properties of Intelligent Spinel Ferrite Nanomaterials (GA19-23647S)

through investigation of correlation among cation distribution, particle size cation distribution and particle size of spinel ferrite nanostructures synthesized knowledge, a detailed, systematic and fundamental study on the correla...

Nano-materials (production and properties)

  • 2019 - 2021
  • 4 865 tis. Kč
  • 4 865 tis. Kč
  • GA ČR
Project

Polyhedral (Car)boranes; Cationic and Catalytically Applicable (GA22-03945S)

Based on our unique approach for the preparation of polyhedral ionic boranes and carboranes with a cluster in the cationic part, a range of these compounds with simple, complex and (car)borane cations will be prepared and used as ca...

Organic chemistry

  • 2022 - 2024
  • 7 803 tis. Kč
  • 7 803 tis. Kč
  • GA ČR
Project

Alkali-metal-cation homeostasis in Saccharomyces cerevisiae biology (GA204/08/0354)

To maintain the homeostasis of intracellular pH and alkali-metal-cation concentration (stable and high K+/Na+ ratio) yeast S. cerevisiae employs more than 10 plasma of mutantslacking different combinations of genes encoding alkali-metal-...

EE - Mikrobiologie, virologie

  • 2008 - 2010
  • 3 102 tis. Kč
  • 3 102 tis. Kč
  • GA ČR
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