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8X23009

Species-specific effect of nucleolus in embryonic development

Public support

  • Provider

    Ministry of Education, Youth and Sports

  • Programme

    Programme for Funding Multilateral Scientific and Technological Cooperation Projects in the Danube Region

  • Call for proposals

  • Main participants

    Univerzita Karlova / Lékařská fakulta v Plzni

  • Contest type

    M2 - International cooperation

  • Contract ID

    -

Alternative language

  • Project name in Czech

    Druhově specifický vliv jadérka v embryonálním vývoji

  • Annotation in Czech

    The first partial goal will analyse the effect of fibrillar sphere origin on embryonic genome activation (EGA). The second goal will analyse nucleologenesis according to origin of fibrillar sphere. The third goal will analyse the changes in chromatin remodeling in bovine embryos after the interspecies nucleolotransfer. The project proposal is built on existing collaboration with institutions – Constantine the Philosopher University in Nitra (SK) and INRAE center in Jouy-en-Josas (FR). The main goal is to support existing cooperation, its intensification and expansion of our research activity via scholarship opportunities at partner institution. The research intention of the common multilateral project is to obtain new knowledge about specific form of the nucleolus – fibrillar sphere (non-membrane nucleus suborganelle).

Scientific branches

  • R&D category

    ZV - Basic research

  • OECD FORD - main branch

    30101 - Human genetics

  • OECD FORD - secondary branch

    30502 - Other medical science

  • OECD FORD - another secondary branch

  • CEP - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    EB - Genetics and molecular biology<br>FP - Other medical fields

Solution timeline

  • Realization period - beginning

    Jul 1, 2023

  • Realization period - end

    Jun 30, 2025

  • Project status

    K - Ending multi-year project

  • Latest support payment

    Feb 14, 2025

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP25-MSM-8X-R

  • Data delivery date

    Mar 5, 2025

Finance

  • Total approved costs

    216 thou. CZK

  • Public financial support

    216 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    0 thou. CZK