Mechanisms and dynamics of macromolecular complexes
Public support
Provider
Ministry of Education, Youth and Sports
Programme
—
Call for proposals
—
Main participants
Jihočeská univerzita v Českých Budějovicích / Přírodovědecká fakulta
Contest type
OP - EU Operational Programme
Contract ID
CZ.02.1.01/0.0/0.0/15_003/0000411
Alternative language
Project name in Czech
Mechanismy a dynamika makromolekulárních komplexů
Annotation in Czech
Projekt objasní mechanismus skládání a fungování velkých makromolekulárních komplexů jako jsou anténní komplexy fotosyntetických pigmentů, roli RNA v replikaci a skládání virů a v regulaci buněčných pochodů, mechanismus rekombinace v leukocytech, mechanismus přestavby chromatinu a fungování membránových komplexů v bakteriích a prvocích.
Scientific branches
R&D category
ZV - Basic research
CEP classification - main branch
EE - Microbiology, virology
CEP - secondary branch
CC - Organic chemistry
CEP - another secondary branch
—
OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)
10401 - Organic chemistry<br>10606 - Microbiology<br>10607 - Virology
Completed project evaluation
Provider evaluation
U - Uspěl podle zadání (s publikovanými či patentovanými výsledky atd.)
Project results evaluation
In the initial phase, there was built a multidisciplinary centre integrating specialised approaches to address common goals. There was deepened a collaboration with other national centres in structural biology, imaging and biophysics. During the project, the established centre provided services in single molecule imaging and biophysics and characterisation of large complex dynamics. The project combined classical structural biology methods such as diffraction and electron microscopy with single molecule biophysics and imaging in living cells. The interdisciplinary approach applied within a closely integrated team of specialists from physics, chemistry and biology has yielded many new insights and resulted in numerous publications. The facilities created during the project have fostered a new generation of scientific and technical staff with a broad knowledge horizon and a problem-oriented approach to the realisation of complex objectives.
Solution timeline
Realization period - beginning
Dec 23, 2016
Realization period - end
Jun 30, 2023
Project status
U - Finished project
Latest support payment
Sep 6, 2020
Data delivery to CEP
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data delivery code
CEP24-MSM-EF-U
Data delivery date
Jul 1, 2024
Finance
Total approved costs
207,410 thou. CZK
Public financial support
194,945 thou. CZK
Other public sources
0 thou. CZK
Non public and foreign sources
10,370 thou. CZK