Leishmania development in phlebotomine sand flies and transmission to the vertebrates: the role of leishmaniaviruses and RNA interference
Public support
Provider
Czech Science Foundation
Programme
Standard projects
Call for proposals
SGA0202600001
Main participants
Ostravská univerzita / Přírodovědecká fakulta
Contest type
VS - Public tender
Contract ID
26-20420S
Alternative language
Project name in Czech
Leishmania development in phlebotomine sand flies and transmission to the vertebrates: the role of leishmaniaviruses and RNA interference
Annotation in Czech
Understanding the molecular aspects of Leishmania-sand fly interactions is highly important for the effective control and prevention of the disease. In the proposed study, we will assess, for the first time, the role of RNA viruses and RNAi mechanisms in regulating Leishmania development in sand flies and their subsequent transmission to the vertebrate hosts. In addition, and, again, for the first time, we will use high-throughput sequencing to link the observed phenotypes to the differences in the insect immune responses.
Scientific branches
R&D category
ZV - Basic research
OECD FORD - main branch
10613 - Zoology
OECD FORD - secondary branch
10607 - Virology
OECD FORD - another secondary branch
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CEP - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)
EE - Microbiology, virology<br>EG - Zoology
Solution timeline
Realization period - beginning
Jan 1, 2026
Realization period - end
Dec 31, 2028
Project status
Z - Beginning multi-year project
Latest support payment
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Data delivery to CEP
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data delivery code
CEP26-GA0-GA-R
Data delivery date
May 19, 2026
Finance
Total approved costs
11,751 thou. CZK
Public financial support
11,751 thou. CZK
Other public sources
0 thou. CZK
Non public and foreign sources
0 thou. CZK