Coupling vapor generation, miniature plasma and Orbitrap MS – on the way to precise and accurate determination of metal and metalloid isotope ratios
Public support
Provider
Czech Science Foundation
Programme
Standard projects
Call for proposals
SGA0202600001
Main participants
Ústav analytické chemie AV ČR, v. v. i.
Contest type
VS - Public tender
Contract ID
26-22432S
Alternative language
Project name in Czech
Coupling vapor generation, miniature plasma and Orbitrap MS – on the way to precise and accurate determination of metal and metalloid isotope ratios
Annotation in Czech
Ultratrace analysis of metals and metalloids is of great importance to identify and track various natural and anthropogenic processes, but also to initiate the remediation to mitigate the human health concerns associated with their toxicity. In recent years, isotope ratio analysis has come to the forefront for monitoring such processes. The aim of the project is to develop new methods for the determination of selected metals (Cr, Mo, W, and Re) and metalloids (Ge and Sb). The methods will effectively combine vapor generation techniques, i.e., hydride generation or photochemical vapor generation, with ambient ionization in a dielectric barrier discharge device, and detection by high-resolution mass spectrometry using an Orbitrap mass analyzer. All three procedures will be optimized with a focus on the sensitive and spectral interference-free total determination of selected analytes (or speciation analysis), but also on the feasibility of their precise and accurate isotope ratio determination. The methods will be validated by measurement of reference materials or real samples.
Scientific branches
R&D category
ZV - Basic research
OECD FORD - main branch
10406 - Analytical chemistry
OECD FORD - secondary branch
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OECD FORD - another secondary branch
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CEP - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)
CB - Analytical chemistry, separation
Solution timeline
Realization period - beginning
Jan 1, 2026
Realization period - end
Dec 31, 2028
Project status
Z - Beginning multi-year project
Latest support payment
—
Data delivery to CEP
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data delivery code
CEP26-GA0-GA-R
Data delivery date
Apr 27, 2026
Finance
Total approved costs
8,994 thou. CZK
Public financial support
8,994 thou. CZK
Other public sources
0 thou. CZK
Non public and foreign sources
0 thou. CZK