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Mito-nuclear co-evolution and its consequences for species identification by DNA barcoding

Public support

  • Provider

    Czech Science Foundation

  • Programme

    Standard projects

  • Call for proposals

    SGA0202600001

  • Main participants

    Ústav biologie obratlovců AV ČR, v. v. i.

  • Contest type

    VS - Public tender

  • Contract ID

    26-23521S

Alternative language

  • Project name in Czech

    Mito-nuclear co-evolution and its consequences for species identification by DNA barcoding

  • Annotation in Czech

    The close link between products of mitochondrial (mt) and nuclear (N-mt) genes functioning in mitochondria is a basis of the so-called mito-nuclear compatibility species concept and species identification based on mtDNA barcoding. In this project we will use unprecedented genomic data on African small mammals (mainly murid rodents, but not only) to test the predictions derived from the co-evolution between mtDNA and N-mt genes. Specifically, we will analyse the type of selection working on genes involved in crucial processes in mitochondria (e.g. oxidative phosphorylation) and we will review the cases and circumstances of interspecific mtDNA introgression. In selected examples, we will study in more details the level of co-introgression of N-mt genes. Finally, we plan to produce new genomic data from selected taxa and analyse the evolution of NUMTs (= nuclear copies of mtDNA fragments). All these steps should significantly improve the reliability of using mtDNA barcodes in simple species identification.

Scientific branches

  • R&D category

    ZV - Basic research

  • OECD FORD - main branch

    10613 - Zoology

  • OECD FORD - secondary branch

    10619 - Biodiversity conservation

  • OECD FORD - another secondary branch

    10603 - Genetics and heredity (medical genetics to be 3)

  • CEP - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    EB - Genetics and molecular biology<br>EG - Zoology<br>EH - Ecology - communities

Solution timeline

  • Realization period - beginning

    Jan 1, 2026

  • Realization period - end

    Dec 31, 2028

  • Project status

    Z - Beginning multi-year project

  • Latest support payment

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP26-GA0-GA-R

  • Data delivery date

    Apr 30, 2026

Finance

  • Total approved costs

    10,842 thou. CZK

  • Public financial support

    10,842 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    0 thou. CZK