Mitochondrial responses to seasonal cold acclimation and acute cold stress in Drosophila.
Public support
Provider
Czech Science Foundation
Programme
Standard projects
Call for proposals
SGA0202600001
Main participants
Biologické centrum AV ČR, v. v. i.
Contest type
VS - Public tender
Contract ID
26-21756S
Alternative language
Project name in Czech
Mitochondrial responses to seasonal cold acclimation and acute cold stress in Drosophila.
Annotation in Czech
This project will provide a comprehensive analysis of previously unknown adaptive changes in mitochondrial physiology that accompany the seasonal phenotypic switch in cold temperate and boreal insect species. Virtually everything we know about insect mitochondria relates to the active summer phenotype. Very little is known about how mitochondria switch from being an engine to support a vigorous summer metabolism (including flight) to a system to maintain a slow basal metabolism and to ensure survival at extremely low temperatures for long periods of the boreal winter. The project will compare changes in mitochondrial physiology induced by short photoperiod and cold acclimation in selected Drosophila species occurring beyond Arctic Circle with changes in tropical species and those that have recently colonised temperate zone. We will use an integrative approach combining microscopy of mitochondrial morphology, physiology of respiratory complexes, measurement of metabolic activities at tissue and whole organism levels, metabolomic and proteomic profiling, and functional experiments.
Scientific branches
R&D category
ZV - Basic research
OECD FORD - main branch
10602 - Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology
OECD FORD - secondary branch
10616 - Entomology
OECD FORD - another secondary branch
10620 - Other biological topics
CEP - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)
EA - Morphology and cytology<br>EG - Zoology
Solution timeline
Realization period - beginning
Jan 1, 2026
Realization period - end
Dec 31, 2028
Project status
Z - Beginning multi-year project
Latest support payment
—
Data delivery to CEP
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data delivery code
CEP26-GA0-GA-R
Data delivery date
Apr 30, 2026
Finance
Total approved costs
9,908 thou. CZK
Public financial support
9,908 thou. CZK
Other public sources
0 thou. CZK
Non public and foreign sources
0 thou. CZK