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Novel pathways of FGFR3 signaling in achondroplasia

Public support

  • Provider

    Czech Science Foundation

  • Programme

    Standard projects

  • Call for proposals

    Standardní projekty 12 (SGA02009GA-ST)

  • Main participants

  • Contest type

    VS - Public tender

  • Contract ID

    301/09/0587

Alternative language

  • Project name in Czech

    Nové dráhy FGFR3 signalingu v achondroplázii

  • Annotation in Czech

    Cílem projektu je objevit nové signální dráhy FGFR3 receptorové tyrozin-kinázy v chrupavce metodou skríningu molekulární knihovny. Účelem projektu je (A) objasnění mechanizmu patologického FGFR3 signalingu v achondroplázii a (B) identifikace potenciálních možností léčby tohoto onemocnění.

Scientific branches

  • R&D category

    ZV - Basic research

  • CEP classification - main branch

    EB - Genetics and molecular biology

  • CEP - secondary branch

    FP - Other medical fields

  • CEP - another secondary branch

    ED - Physiology

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    10603 - Genetics and heredity (medical genetics to be 3)<br>10604 - Reproductive biology (medical aspects to be 3)<br>10605 - Developmental biology<br>10608 - Biochemistry and molecular biology<br>10609 - Biochemical research methods<br>30101 - Human genetics<br>30105 - Physiology (including cytology)<br>30106 - Anatomy and morphology (plant science to be 1.6)<br>30107 - Medicinal chemistry<br>30108 - Toxicology<br>30109 - Pathology<br>30221 - Critical care medicine and Emergency medicine<br>30223 - Anaesthesiology<br>30224 - Radiology, nuclear medicine and medical imaging<br>30225 - Allergy<br>30226 - Rheumatology<br>30227 - Geriatrics and gerontology<br>30229 - Integrative and complementary medicine (alternative practice systems)<br>30230 - Other clinical medicine subjects<br>30307 - Nursing<br>30308 - Nutrition, Dietetics<br>30309 - Tropical medicine<br>30310 - Parasitology<br>30311 - Medical ethics<br>30312 - Substance abuse<br>30501 - Forensic science<br>30502 - Other medical science

Completed project evaluation

  • Provider evaluation

    V - Vynikající výsledky projektu (s mezinárodním významem atd.)

  • Project results evaluation

    The project was excellent, both in terms of expertise and in terms of disbursement of funds.

Solution timeline

  • Realization period - beginning

    Mar 1, 2009

  • Realization period - end

    Dec 31, 2011

  • Project status

    U - Finished project

  • Latest support payment

    Apr 16, 2011

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP12-GA0-GA-U/02:2

  • Data delivery date

    May 2, 2016

Finance

  • Total approved costs

    2,850 thou. CZK

  • Public financial support

    2,850 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    0 thou. CZK