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Effect of synthetic cytokinin analogues on plant hormone perception, metabolism and phenotypic alterations

Project goals

Synthetic derivatives of plant hormones cytokinins tested so far in our laboratory affect cytokinin degradation by cytokinin dehydrogenase and/or cytokinin perception by receptors in vitro. The objective of proposed project is screening of developmentalchanges after application of selected cytokinin analogues to plants which will be accompanied by detailed study of expression of genes involved in cytokinin biosynthesis, perception and deactivation as well as by monitoring level of cytokinin metabolitesand auxins. Newly synthesized cytokinin analogues and compounds acting as inhibitors of cytokinin biosynthesis will be also tested. In addition, an alternative mechanism of cytokinin deactivation by xanthine dehydrogenase will be verified and physiological function of non-secreted cytokinin dehydrogenase AtCKX7 will be elucidated. Developmental changes triggered by different compounds can be used to study distinct metabolic pathways involved in cytokinin homeostasis and the compounds may find an application for improvement of yield attributes of agricultural crops.

Keywords

cytokininmetabolismuscytokinindehydrogenasareceptor

Public support

  • Provider

    Czech Science Foundation

  • Programme

    Standard projects

  • Call for proposals

    Standardní projekty 11 (SGA02008GA-ST)

  • Main participants

  • Contest type

    VS - Public tender

  • Contract ID

    522/08/0920

Alternative language

  • Project name in Czech

    Vliv syntetických derivátů cytokininů na percepci a metabolismus rostlinných hormonů a fenotypické změny

  • Annotation in Czech

    Cílem projektu je studovat vývoj rostliny, expresi genů metabolismu cytokininů (CK) a hladiny CK a auxinů po aplikaci derivátů CK, testovat nová analoga CK a inhibitory biosyntézy, ověřit alternativní mechanismus deaktivace CK a zkoumat fyziologickou funkci nesekretované cytokinindehydrogenasy.

Scientific branches

  • R&D category

    ZV - Basic research

  • CEP classification - main branch

    ED - Physiology

  • CEP - secondary branch

    CE - Biochemistry

  • CEP - another secondary branch

    EB - Genetics and molecular biology

  • 10603 - Genetics and heredity (medical genetics to be 3)
    10604 - Reproductive biology (medical aspects to be 3)
    10605 - Developmental biology
    10608 - Biochemistry and molecular biology
    10609 - Biochemical research methods
    30101 - Human genetics
    30105 - Physiology (including cytology)

Completed project evaluation

  • Provider evaluation

    V - Vynikající výsledky projektu (s mezinárodním významem atd.)

  • Project results evaluation

    The project was excellent, both in terms of expertise and in terms of disbursement of funds.

Solution timeline

  • Realization period - beginning

    Jan 1, 2008

  • Realization period - end

    Dec 31, 2011

  • Project status

    U - Finished project

  • Latest support payment

    Apr 16, 2011

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP12-GA0-GA-U/02:2

  • Data delivery date

    May 2, 2016

Finance

  • Total approved costs

    5,498 thou. CZK

  • Public financial support

    5,498 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    0 thou. CZK