Deciphering subgenome differentiation and centromere dynamics in asymmetric meiosis of dogroses
Public support
Provider
Czech Science Foundation
Programme
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Call for proposals
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Main participants
Biofyzikální ústav AV ČR, v. v. i.
Contest type
M2 - International cooperation
Contract ID
26-24510L
Alternative language
Project name in Czech
Deciphering subgenome differentiation and centromere dynamics in asymmetric meiosis of dogroses
Annotation in Czech
Polyploidy is common in land plants having strong impact on meiotic cell division and recombination. In allopolyploid dogroses (Rosa sect. Caninae), meiotic cell division is asymmetric. Members of the section are tetra- to heptaploid (2n = 4x, 5x, 6x, 7x = 28, 35, 42, 49) with pentaploids being most abundant. At each ploidy level two chromosome sets form bivalents and are biparentally inherited, while the remaining univalent-forming subgenomes are transmitted only through the egg cell. The Canina meiosis of dogroses is unique among eukaryotes. Based on our previous research, in this project we aim to characterize centromere compositions and chromosome segregation in Canina meiosis in dogroses and closely related diploids. By using comparative genomics in combination with high-resolution cytogenetics, we will reveal epigenetic regulations of biparentally and uniparentally inherited centromeres and identify the subgenomes involved in pairing, and recombination. Employing mRNA Seq we will uncover gene expression at organ specific manner and identify candidate meiotic genes.
Scientific branches
R&D category
ZV - Basic research
OECD FORD - main branch
10611 - Plant sciences, botany
OECD FORD - secondary branch
10605 - Developmental biology
OECD FORD - another secondary branch
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CEP - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)
EB - Genetics and molecular biology<br>EF - Botany
Solution timeline
Realization period - beginning
Jan 1, 2026
Realization period - end
Dec 31, 2028
Project status
Z - Beginning multi-year project
Latest support payment
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Data delivery to CEP
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data delivery code
CEP26-GA0-GF-R
Data delivery date
May 23, 2026
Finance
Total approved costs
6,359 thou. CZK
Public financial support
6,305 thou. CZK
Other public sources
54 thou. CZK
Non public and foreign sources
0 thou. CZK