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Novel aspects of signalling in bone related cells

Public support

  • Provider

    Ministry of Education, Youth and Sports

  • Programme

    INTER-EXCELLENCE

  • Call for proposals

    SMSM2020LTC01

  • Main participants

    Ústav živočišné fyziologie a genetiky AV ČR, v. v. i.

  • Contest type

    VS - Public tender

  • Contract ID

    MSMT-21080/2020-23

Alternative language

  • Project name in Czech

    Novel aspects of signalling in bone related cells

  • Annotation in Czech

    Despite relatively broad and still increasing knowledge in the cell signalling, new pathways or components are emerging and this applies to bone cells as well. With support of the running COST Action and international cooperation, the project aims to elucidate the molecular machinery and new functions involved in the signalling related to molecules such as CD95/CD178 and Myb. The project aims to integrate the most recent findings obtained in frame of research in the applicant´s lab with objectives of the running COST Action in order to expand the results using new approaches and to extend scientific outcomes. The contribution to the network will include new partners to accelerate and improve research with respect to explanation of new mechanisms of molecular signalling in bone-related cells.

Scientific branches

  • R&D category

    ZV - Basic research

  • OECD FORD - main branch

    10603 - Genetics and heredity (medical genetics to be 3)

  • OECD FORD - secondary branch

    30502 - Other medical science

  • OECD FORD - another secondary branch

    10608 - Biochemistry and molecular biology

  • CEP - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    CE - Biochemistry<br>EB - Genetics and molecular biology<br>FP - Other medical fields

Completed project evaluation

  • Provider evaluation

    V - Vynikající výsledky projektu (s mezinárodním významem atd.)

  • Project results evaluation

    The project ran according to the approved schedule (prolonged in 2023 due to covid-19 compensations), including the relevant outcomes: successful integration with the COST Action, presentation of the scientific results at an prestigious international conference (US) and abstracts were published in IF journals ranked within the Q1 category. Also the key outcomes in form of original papers were published in IF journals (IF above 5) ranked in Q1 category.

Solution timeline

  • Realization period - beginning

    Oct 1, 2020

  • Realization period - end

    Sep 10, 2023

  • Project status

    U - Finished project

  • Latest support payment

    Feb 17, 2023

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP24-MSM-LT-U

  • Data delivery date

    Jul 1, 2024

Finance

  • Total approved costs

    4,424 thou. CZK

  • Public financial support

    4,424 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    0 thou. CZK