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NR9284

Terlipressin in the treatment of catecholamine-resistant septic shock

Public support

  • Provider

    Ministry of Health

  • Programme

    Departmental Programme of Research and Development - MH II from 2008 to 2011

  • Call for proposals

    VaV pro Ministerstvo zdravotnictví 4 (SMZ02007NR)

  • Main participants

  • Contest type

    VS - Public tender

  • Contract ID

    NR9284-4/2007

Alternative language

  • Project name in Czech

    Terlipresin v léčbě septického šoku rezistentního na katecholaminy

  • Annotation in Czech

    Studie zkoumající využití nového postupu v léčbě septického šoku resistentního na katecholaminy u kriticky nemocných. Studie pokoušející se o normalizaci hemodynamické situace u pacientů v septickém šoku s orgánovým selháním v důsledku těžké sepse.

Scientific branches

  • R&D category

    NV - Nonindustrial research (Applied research excluded Industrial research)

  • CEP classification - main branch

    FI - Traumatology and orthopaedics

  • CEP - secondary branch

    FJ - Surgery including transplantology

  • CEP - another secondary branch

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    30211 - Orthopaedics<br>30212 - Surgery<br>30213 - Transplantation

Completed project evaluation

  • Provider evaluation

    V - Vynikající výsledky projektu (s mezinárodním významem atd.)

  • Project results evaluation

    Experimental model of septic shock was evolved. Terlipressin WAS NOT EFFECTIVE in shock treatment. No correlation was found between vasopresin level and effect of terlipressin. In advanced shock addition of terlipressin to norepinephrin is not effective.

Solution timeline

  • Realization period - beginning

    Jan 1, 2007

  • Realization period - end

    Dec 31, 2010

  • Project status

    U - Finished project

  • Latest support payment

    Dec 18, 2009

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP11-MZ0-NS-U/04:2

  • Data delivery date

    Jan 10, 2012

Finance

  • Total approved costs

    6,135 thou. CZK

  • Public financial support

    5,782 thou. CZK

  • Other public sources

    228 thou. CZK

  • Non public and foreign sources

    125 thou. CZK