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1 450 (0,072s)

Project

Study of apoptosis inhibitors as diagnostic and predictive tumor biomarkers in lung cancer (NR7860)

Analysis of expression of apoptosis inhibitors by molecular and biochemical methods in tumor tissue, lung parenchyma, biopsy and cytological samples and sputum from lung cancer patients and study of their significance as tumor b...

FD - Onkologie a hematologie

  • 2004 - 2008
  • 9 173 tis. Kč
  • 8 553 tis. Kč
  • MZ
Project

Looking for biomarkers of upper gastrointestinal tract tumors by the use of proteomic profiling. (NT14282)

. The prognosis of patients with tumors of the upper GIT is uncertain and treatment options are limited. Currently, there is intensive search for biomarkers that allow early of patients with cancers of the upper GIT. Intraoperative ...

FJ - Chirurgie včetně transplantologie

  • 2013 - 2015
  • 6 056 tis. Kč
  • 6 056 tis. Kč
  • MZ
Project

Identification of new diagnostic/predictive biomarkers and compounds applicable to personalized treatments of multidrug resistant tumors (LTC19020)

The aim of this project is identification and validation of new prognostic and predictive molecular biomarkers of multidrug resistence in solid tumors. New molecular biomarkers will be characterized in detail by analysis o...

Human genetics

  • 2019 - 2022
  • 3 936 tis. Kč
  • 3 936 tis. Kč
  • MŠMT
Project

Development of microRNA-based biomarkers for diagnostics of cancer chemoresistance (TH04010303)

related to cancer diseases and chemoresistance of tumors. Selected miRNA biomarkers biomarkers and their use for early diagnosis of certain types of cancer and prediction of chemoresistance of tumor to convention...

Technologies involving identifying the functioning of DNA, proteins and enzymes and how they influence the onset of disease and maintenance of well-being (gene-based diagnostics and therapeutic interventions [pharmacogenomics, gene-based therapeutics])

  • 2019 - 2021
  • 9 748 tis. Kč
  • 5 630 tis. Kč
  • TA ČR
Project

Predicting response to checkpoint inhibitors using complex molecular characteristic and immunoprofiling in solid tumors. (NV18-03-00339)

. The checkpoint inhibitors efficacy is not limited to the tumor tissue-type, but is evident in the broad range of solid tumors (malignant melanoma, lung, kidney, bladder, head and neck, esophageal, stomach cancer, MSI tumors

Oncology

  • 2018 - 2022
  • 11 925 tis. Kč
  • 11 887 tis. Kč
  • MZ
Project

Biomarkers mapping at the infiltration zone of glioblastomas and their topographic relationship to an early relapse. (NU23-03-00100)

/ at resection margins and to correlate the biomarkers with patterns of early progression. Better understanding of the residual disease and tumor biomarkers at the tumor based on the analyses of a tumor c...

Oncology

  • 2023 - 2026
  • 13 669 tis. Kč
  • 13 669 tis. Kč
  • MZ
Project

Circulating microvesicles (microparticles and exosomes) for diagnosis of gynecological malignancies (NT12248)

Reliable biomarkers are needed to improve diagnosis and therapy. These microvesicles carry proteins and miRNA that would be useful as specific tumor markers. To identify cancer specific biomarkers we propose to combine mole...

FK - Gynekologie a porodnictví

  • 2011 - 2015
  • 6 321 tis. Kč
  • 6 321 tis. Kč
  • MZ
Project

New semiconductor glyco-biosensors for selective detection of galectin biomarkers of brain cancer (LUC24024)

The main goal of the project is to develop and validate new biosensors as diagnostic tools for the future stratification of patients with brain tumors.......

Analytical chemistry

  • 2024 - 2027
  • 9 998 tis. Kč
  • 9 998 tis. Kč
  • MŠMT
Project

Molecular portraits of major morphological components of colon tumors (GA19-08646S)

Intra-tumor heterogeneity (ITH) is a major hurdle towards designing of whole-genome expression profiles within primary colon tumors. Expression profiles extracted from morphologically well-defined regions within tumors will...

Oncology

  • 2019 - 2022
  • 7 244 tis. Kč
  • 6 853 tis. Kč
  • GA ČR
Project

Analysis of interactions between tumor cells and microenvironment using mass cytometry and protein arrays (NV15-26588A)

and in brain tumors as a model). Last, useful biomarkers will be built into single cells) that contain a tumor infiltration. The approach would combine and complement two innovative”) to determine changes in cellular compo...

FD - Onkologie a hematologie

  • 2015 - 2018
  • 18 817 tis. Kč
  • 18 817 tis. Kč
  • MZ
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