Filtry
Fibromyxoid aSoft Tissue Tumor With PLAG1 Fusion-The First Case in an Adult Patient
the pleomorphic adenoma gene 1 (PLAG1) and its partner. PLAG1 gene fusions were previously tumors, uterine epitheloid, myxoid leiomyosarcomas, and, recently, with PLAG1 of a soft tissue tumor with a PLAG1 fusion g...
Pathology
- 2024 •
- Jimp •
- Odkaz
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Jimp - Článek v periodiku v databázi Web of Science
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What is hiding behind S100 protein and SOX10 positive oncocytomas? Oncocytic pleomorphic adenoma and myoepithelioma with novel gene fusions in a subset of cases
protein and/or SOX10, respectively. Fusion transcripts CHCHD7-PLAG1 and GEM-PLAG1 were and PLAG1 break-apart FISH probe, respectively. Another five cases were positive for PLAG1 rearrangement by FISH. In the contr...
Pathology
- 2020 •
- Jimp •
- Odkaz
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Jimp - Článek v periodiku v databázi Web of Science
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Molecular Profiling of Clear Cell Myoepithelial Carcinoma of Salivary Glands With EWSR1 Rearrangement Identifies Frequent PLAG1 Gene Fusions But No EWSR1 Fusion Transcripts
cases (6/15, 40%), including LIFR-PLAG1 and CTNNB1-PLAG1, in 2 cases each, and CHCHD7-PLAG1 and EWSR1-ATF1 fusions were identified in 1 case each. Seven cases, including those with PLAG1 fusion, were positive for ...
Biochemistry and molecular biology
- 2021 •
- Jimp •
- Odkaz
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Jimp - Článek v periodiku v databázi Web of Science
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Novel ZEB2-PLAG1 fusion gene identified by RNA sequencing in a case of lipoblastoma
of recurrence than ordinary lipoblastoma. We describe four different PLAG1 gene fusion...
Oncology
- 2021 •
- Jimp •
- Odkaz
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Jimp - Článek v periodiku v databázi Web of Science
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Calcifying Spindle Cell Soft Tissue Tumor With SOX10::PLAG1 Fusion: A Case Report of a Morphologically Distinctive and Potentially Novel Soft Tissue Tumor
to the identification of several tumor types with PLAG1 gene fusions some of which also affect were present. Targeted NGS revealed a SOX10::PLAG1 fusion and fluorescent in situ hybridization confirmed the presence of PLAG1...
Pathology
- 2024 •
- Jimp •
- Odkaz
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Jimp - Článek v periodiku v databázi Web of Science
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Chromosome Translocations, Gene Fusions, and Their Molecular Consequences in Pleomorphic Salivary Gland Adenomas
in gene fusions involving the transcription factor genes PLAG1 and HMGA2. Until by mutations in IGF2/HMGA2/PLAG1, have provided new clues to the understanding regulator of PLAG1 and that HMGA2 regulates the expression of I...
Pathology
- 2022 •
- Jimp •
- Odkaz
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Jimp - Článek v periodiku v databázi Web of Science
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PLAG1-Rearranged Uterine Sarcomas: A Study of 11 Cases Showing a Wide Phenotypical Spectrum Not Limited to Myxoid Leiomyosarcoma-like Morphology
PLAG1 gene fusions were recently identified in a subset of uterine myxoid leiomyosarcomas (M-LMS). However, we have encountered cases of PLAG1-rearranged uterine sarcomas (PLAG1-US) lacking M-LMS-like morphology and/or any ...
Pathology
- 2024 •
- Jimp •
- Odkaz
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Jimp - Článek v periodiku v databázi Web of Science
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Expanding the Molecular Spectrum of Carcinoma Ex Pleomorphic Adenoma: An Analysis of 84 Cases With a Novel HMGA2::LINC02389 Fusion
identified in 12/16 (75%) CXPA, including LIFR::PLAG1, CTNNB1::PLAG1, FGFR1::PLAG1 PLAG1 (6/11) and HMGA2 (1/1) gene break probes. Split signals indicating gene break were identified by FISH for PLAG1 (12...
Pathology
- 2024 •
- Jimp •
- Odkaz
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Jimp - Článek v periodiku v databázi Web of Science
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Primary cardiac lipoblastoma of the right atrium
Lipoblastoma is a rare neoplasm of the embryonal white fat. It occurs most commonly in children under the age of 3 years and usually inflicts the superficial soft tissues of trunk and extremities. We present the case of a 3-year-old male patient with...
Pathology
- 2023 •
- Jimp •
- Odkaz
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Jimp - Článek v periodiku v databázi Web of Science
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Lipoblastoma-like tumor of the vulva: a clinicopathologic, immunohistochemical, fluorescence in situ hybridization and genomic copy number profiling study of seven cases
evaluated PLAG1, HMGA2, and RB1 immunohistochemistry and DDIT3 rearrangement status-like tumor, we examined 7 cases by RB1 immunohistochemistry, DDIT3 and PLAG1 break; pattern of weak and negative nuclear expression in all seven ca...
Pathology
- 2018 •
- Jimp •
- Odkaz
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Jimp - Článek v periodiku v databázi Web of Science
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