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Výsledek výzkumu

Long non-coding RNA exchange during the oocyte-to-embryo transition in mice

remodeling of the long non-coding RNA (lncRNA) pool. Here, we used next generation sequencing and de novo transcript assembly to define the core population of 1,600 lncRNAs expressed during the OET (lncRNAs). Relative to m...

Reproductive biology (medical aspects to be 3)

  • 2017
  • Jimp
  • Odkaz
Výsledek výzkumu

LncRNA profiling reveals that the deregulation of H19, WT1-AS, TCL6, and LEF1-AS1 is associated with higher-risk myelodysplastic syndrome

Although lncRNAs have been increasingly recognized as regulators). By genome-wide profiling, we identified lncRNAs deregulated in various groups of MDS patients. We computationally constructed lncRNA-protein coding gene net...

Hematology

  • 2020
  • Jimp
  • Odkaz
Výsledek výzkumu

The long non-coding RNA landscape in juvenile myelomonocytic leukemia

We documented for the first time the lncRNA landscape in 44 JMML patients and have associated lncRNA expression with clinical and molecular characteristics. We demonstrated that JMML patients exhibit a distinct lncRNA expre...

Hematology

  • 2018
  • Jimp
  • Odkaz
Výsledek výzkumu

Bioinformatic Analysis of Ixodes ricinus Long Non-Coding RNAs Predicts Their Binding Ability of Host miRNAs

RNA (lncRNA) research and characterization. Here, we report for the first time of lncRNAs and showed that lncRNA expression is stable among different studies. While the length distribution of lncRNAs from the indi...

Cell biology

  • 2022
  • Jimp
  • Odkaz
Výsledek výzkumu

Association of lncRNA and transcriptome intersections with response to targeted therapy in metastatic renal cell carcinoma

Long non-coding RNAs (lncRNAs) serve an important role in cancer progression lncRNAs associated with the response to the receptor tyrosine kinase inhibitor carcinoma (mRCC). The gene expression of 84 cancer-associated lncRNAs

Oncology

  • 2023
  • Jimp
  • Odkaz
Výsledek výzkumu

The use of Human Inflammatory Response and Autoimmunity RT2 lncRNA PCR Array for plasma examination in breast cancer patients prior to therapy

Long non-coding RNAs (lncRNAs) are defined as RNA molecules longer than 200 expression. Dysregulations of lncRNAs (e.g. HOTAIR and MALAT I) were detected in plasma for purposes of non-invasive diagnostics therefore the research of p...

Biological sciences

  • 2019
  • Jimp
  • Odkaz
Výsledek výzkumu

Long Non-Coding RNAs And Their Relevance in Cancer

to external stimuli to produce large numbers of long non-coding RNAs (lncRNAs). Genome-wide studies indicate the existence of more than 3,300 lncRNAs. Long non-coding in the field of lncRNAs has been very slow. Nonetheless...

FD - Onkologie a hematologie

  • 2012
  • Jx
  • Odkaz
Výsledek výzkumu

The Role of Long Non-coding RNAs in the BCR-mediated Activation of Malignant B Cells

, it is unclear if long non-coding RNAs (lncRNAs) are involved in BCR signalling. LncRNAs can for transcription factors, or even participate in signal transduction. LncRNAs were shown whether any lncRNAs could be i...

Hematology

  • 2021
  • O
  • Odkaz
Výsledek výzkumu

Retrotransposon-associated long non-coding RNAs in mice and men

-coding RNAs (lncRNAs), which do not encode for proteins. LncRNAs are a dynamically evolving population of genes. While it is not yet clear what fraction of lncRNAs represents functionally important ones, their features imp...

EB - Genetika a molekulární biologie

  • 2016
  • Jx
  • Odkaz
Výsledek výzkumu

LncRNA PVT1 is increased in renal cell carcinoma and affects viability and migration in vitro

and prognosis estimation feasible in clinical practice. Long non-coding RNAs (lncRNAs) have pathology. Methods In this work, we used next-generation sequencing for global lncRNA lncRNAs have been further validated on an in...

Medical laboratory technology (including laboratory samples analysis; diagnostic technologies) (Biomaterials to be 2.9 [physical characteristics of living material as related to medical implants, devices, sensors])

  • 2022
  • Jimp
  • Odkaz
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