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10 580 (0,095s)

Výsledek výzkumu

Cellular Uptake of modified oligonucleotides:fluorescence approach

Cellular Uptake of modified oligonucleotides:fluorescence approach...

BO - Biofyzika

  • 2005
  • Jx
Výsledek výzkumu

Impact of the Guanidium Group on Hybridization and Cellular Uptake of Cationic Oligonucleotides

Impact of the Guanidium Group on Hybridization and Cellular Uptake of Cationic Oligonucleotides...

CC - Organická chemie

  • 2006
  • Jx
Výsledek výzkumu

Cellular Uptake of Phosphorothioate Oligonucleotide Facilitated by Cationic Porphyrin: A Microfluorescence Study

Cellular uptake of modified oligonucleotide by cationic porphyrins...

BO - Biofyzika

  • 2006
  • Jx
Výsledek výzkumu

The cellular uptake of sensitizers bound to cyclodextrin carries

The cellular uptake of sensitizers bound to cyclodextrin carries...

CA - Anorganická chemie

  • 2004
  • Jx
Výsledek výzkumu

Cellular Uptake of Modified Oligonucleotides: Fluorescence Approach

Intracellular uptake and distribution studies of modified oligonucleotides by using of two fluorescence techniques: Fluorescence imaging and time resolved microspectrofluorimetry....

BO - Biofyzika

  • 2004
  • D
Výsledek výzkumu

Time-resolved microspectrofluorometry and fluorescence imaging techniques - Study of porphyrin-mediated cellular uptake of oligonucleotides

Time-resolved confocal microspectrofluorometry and fluorescence microscopy imaging were applied to monitor the cellular uptake of fluorescent-labeled oligonucleotides delivered by a porphyrin molecule....

BO - Biofyzika

  • 2008
  • Jx
Výsledek výzkumu

Prion protein modulates cellular iron uptake: a novel function with implications for prion disease pathogenesis

The article demonstrates that over-expression of PrPC increases intra-cellular iron. Neither PrPC nor the mutant PrP forms influence the rate or amount of iron released into the medium, suggesting a functional role for PrPC in cellular

EB - Genetika a molekulární biologie

  • 2009
  • Jx
Výsledek výzkumu

The cellular uptake of sensitizers bound to cyclodextrin carriers

Photodynamic therapy of cancers uses the interaction of sensitizers and light to destroy cancer cells. In this study we tested the cellular uptake of meso-tetrakis (4-sulfonatophenyl) porphine (TPPS4) and its complex PdTPPS4 in the ...

BO - Biofyzika

  • 2004
  • Jx
Výsledek výzkumu

Cholesterol conjugated oligonucleotide and LNA: A comparison of cellular and nuclear uptake by Hep2 cells enhanced by Streptolysin-O

therapy, but major limiting factors for their routine use are inefficient cellular uptake and low accessibility to the target sites. Adding various lipophilic studied the cellular delivery of various ON modifications, as w...

EB - Genetika a molekulární biologie

  • 2005
  • Jx
Výsledek výzkumu

Functionalization of osmium arene anticancer complexes with (poly)arginine: Effect on cellular uptake, internalization, and cytotoxicity

Os complexes conjugated to Arg5 and Arg8 increase Os uptake into A2780 human ovarian cancer cells by 2x and 10x, respectively. A 15-fold increase in binding of Os to DNA was observed for Arg8. The complexes exhibited an ability to precipitat...

BO - Biofyzika

  • 2011
  • Jx
  • Odkaz
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