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569 (0,103s) •

Project

Identification of novel molecular pathways involved in the process of B-cell allelic exclusion; chronic lymphocytic leukemia as the model system (NS9652)

rearrangements have been observed, a process referred to as allelic inclusion. CLL exhibiting allelic inclusion represents a unique model to study the process of allelic, allelic inclusion

FD - Onkologie a hematologie

  • 2008 - 2011
    • •
  • 8 112 tis. Kč
    • •
  • 8 082 tis. Kč
    • •
  • MZ
Project

Immunogenetics of lung inflammation VNTR polymorphims of IL-1RA (IL-1 receptor antagonist) gene and pulmonary fibrosis (idiopathic, secondary) (GA310/99/1676)

is to investigate if allele 2 of IL-1RA gene determines an "immunological phenotype" leadingto associated with rheumatological disease we wish to investigate if allele 2 affects to study if allele 2 is a susceptibility fac...

EC - Imunologie

  • 1999 - 2001
    • •
  • 597 tis. Kč
    • •
  • 597 tis. Kč
    • •
  • GA ČR
Project

Apolipoprotein E genotype in relation to the course and outome of severe traumatic brain injury in children. (NS9847)

that the possesion of Apolipoprotein E epsilon 4 allele in children is associated with more intracerebral traumatic lesions detected by CT or MRI, diffuse axonal injuries inclusive. The relationship between different allele

FH - Neurologie, neurochirurgie, neurovědy

  • 2008 - 2010
    • •
  • 644 tis. Kč
    • •
  • 644 tis. Kč
    • •
  • MZ
Project

Analysis of haplotypes in wild and wild-derived mice on chromosome 17 (IAA5052406)

for alleles/genotypes and their combinations on a single chromosome of a given individual. domesticus and M. m. musculus to estimate the number of alleles. In pilot experiments, the haplotype structure of wild-derived strains will ...

EB - Genetika a molekulární biologie

  • 2004 - 2008
    • •
  • 3 396 tis. Kč
    • •
  • 2 146 tis. Kč
    • •
  • AV ČR
Project

Detection and characterization of "blank" HLA class 1 alleles in the Czech population. Implications for transplant medicine (NM6522)

Examination of "blank" HLA class I alleles - using DNA sequencing and flow cytometry to determine their frequency and to analyze HLA molecule expression on cell surface - in the healthy Czech population and in patients awaiting organ transpl...

EB - Genetika a molekulární biologie

  • 2001 - 2003
    • •
  • 2 749 tis. Kč
    • •
  • 2 583 tis. Kč
    • •
  • MZ
Project

Function study of allelic variants of urate transporters in primary hyperuricemia and gout (NV15-26693A)

The aim of our study is to clarify the frequency, the role and the function effect of selected allelic variants of urate transportosome to the serum uric acid normouricemia controls). Selected allelic variants (genotyping of ten gen...

FP - Ostatní lékařské obory

  • 2015 - 2019
    • •
  • 9 818 tis. Kč
    • •
  • 9 818 tis. Kč
    • •
  • MZ
Project

Characterization of novel high-molecular-weight glutenin subunits in synthetic wheats and resistance to leaf diseases (MEB0810001)

Characterisation of potentially new HMW glutenin subunits detected in population of synthetic wheat using electrophoresis. The wheat (Triticum aestivum L.) lines with unknown alleles for the storage proteins will be multiply and also if pote...

EB - Genetika a molekulární biologie

  • 2010 - 2011
    • •
  • 106 tis. Kč
    • •
  • 106 tis. Kč
    • •
  • MŠMT
Project

Impact of genetic factors modifying risk of chronic liver failure on better classification of its aetiology in PiZ SERPINA1 heterozygotes and homozygotes (NU22-06-00103)

allele associated with liver injury is Z allele (rs28929474) but only a minority in Z allele carriers is driven by genetic modifier(s). In our preliminary study, we significantly higher frequency of PNPLA3 rs738409 G a...

Gastroenterology and hepatology

  • 2022 - 2025
    • •
  • 3 710 tis. Kč
    • •
  • 3 710 tis. Kč
    • •
  • MZ
Project

The effect of haplotypes on the expression of thalassemic alleles and their clinical manifestation. (IZ2639)

FG - Pediatrie

  • 1995 - 1997
    • •
  • 1 411 tis. Kč
    • •
  • 1 395 tis. Kč
    • •
  • MZ
Project

Transnational migration and digital inclusion (GA24-11907S)

of digital inclusion between individuals and groups we do not know if and how inclusion and transnational migration. We integrate and extend theories of digital inclusion and transnationalism through a practice theory fram...

Cultural and economic geography

  • 2024 - 2026
    • •
  • 3 788 tis. Kč
    • •
  • 3 788 tis. Kč
    • •
  • GA ČR
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