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5 408 (0,125s) •

Project

Solid-phase synthesis of diversely constrained peptidomimetics. (GAP207/12/0473)

and expeditious solid-phase synthesis of diversely constrained peptidomimetics with complete during traditional Merrifield solid-phase synthesis without a need to prepare dedicated building block...

CC - Organická chemie

  • 2012 - 2014
    • •
  • 9 375 tis. Kč
    • •
  • 9 175 tis. Kč
    • •
  • GA ČR
Project

Green solid phase organic synthesis (GJ18-17978Y)

be replaced with green alternatives. Solid-phase synthesis is a method in drug discovery methodology for solid phase synthesis. The compatibility of selected green solvents will be tested in pept...

Organic chemistry

  • 2018 - 2020
    • •
  • 3 228 tis. Kč
    • •
  • 3 228 tis. Kč
    • •
  • GA ČR
Project

Solid-phase synthesis of drug-like molecules (7AMB14AR031)

The research group at the National University of Rosario (UNR), Rosario, Argentina has been involved in design and synthesis of drug-like molecules with particular interest in transition metals catalysis on solid phase, esp...

CC - Organická chemie

  • 2014 - 2015
    • •
  • 320 tis. Kč
    • •
  • 320 tis. Kč
    • •
  • MŠMT
Project

*Production of the peptidic substance Lecirelin for production of the farmaceutical agent (FR-TI4/804)

*A new method for production of the peptide hormone Lecirelin will be developed. Lecirelin will be used for veterinary purposes. The production will be done on solid phase using both Boc and Fmoc strategies. Purification methods emp...

CC - Organická chemie

  • 2012 - 2014
    • •
  • 17 501 tis. Kč
    • •
  • 8 730 tis. Kč
    • •
  • MPO
Project

Phase diagrams of nanoalloys, their calculations and verifications (LD11046)

will cover materials with full solubility in solid and in liquid phase (Cu-Ni) and with partial solubility in solid phase (Ag-Cu). Materials with intermetallicsThe aim of the project is to extend knowledge on poly...

BJ - Termodynamika

  • 2011 - 2014
    • •
  • 1 750 tis. Kč
    • •
  • 1 750 tis. Kč
    • •
  • MŠMT
Project

Anomeric D- and L-oligonucleotides with isopolar, isosteric internucleotide linkage Synthesis, hybridization properties and spectroscopy (IAA4055902)

to appropriate phosphonate nucleotide analogs, 2)solid-phase synthesis of related for phosphotriester solid-phase oligonucleotide synthesis. Obtained oligonucleotidesProject is directed towards <...

CC - Organická chemie

  • 1999 - 2001
    • •
  • 5 127 tis. Kč
    • •
  • 2 445 tis. Kč
    • •
  • AV ČR
Project

The novel type of oligonucleotides composed of pyrrolidine nucleosides and enzymaticaly stable phosphonate internucleotide bond (GP203/02/D150)

will be evaluated. It isnecessary to manage a synthesis of suitable monomers for solid phase synthesis of the modified oligonucleotides. Tartaric acid would be the key starting and then to the appropriate phosphon...

CC - Organická chemie

  • 2002 - 2005
    • •
  • 2 132 tis. Kč
    • •
  • 704 tis. Kč
    • •
  • GA ČR
Project

Growth of nanofiltration layers from colloidal solutions. Effect of electrochemical properties of colloidal solutions on kinetics of the layer growth. (GA203/05/0846)

steps participate in total synthesis: transport of subcolloidal particles, sticking of particles to a solid phase, transformation of sticked particles to a consolidated phase colloidal particle and the surface cha...

CA - Anorganická chemie

  • 2005 - 2007
    • •
  • 708 tis. Kč
    • •
  • 708 tis. Kč
    • •
  • GA ČR
Project

Synthesis and mechanism of action of triterpenoids with antitumor activities. (GA15-05620S)

active compounds. We want to optimize synthesis of triterpenes on solid phase and synthesis of the most promissing structures will be optimized in large scale......

CE - Biochemie

  • 2015 - 2017
    • •
  • 5 868 tis. Kč
    • •
  • 5 868 tis. Kč
    • •
  • GA ČR
Project

Combinatorial chemistry in research and education (EE2.3.20.0009)

The aim is to establish research team that will deal with solid-phase synthesis and combinatorial chemistry. The new team will develop a modern chemical methods and instrumental tools for the preparation of chemical librari...

CB - Analytická chemie, separace

  • 2011 - 2014
    • •
  • 21 446 tis. Kč
    • •
  • 21 446 tis. Kč
    • •
  • MŠMT
  • 1 - 10 out of 5 408