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85 (0,094s) •

Project

Obesity, diabetes and neurodegeneration crosstalk New therapeutic potential of prolactin-releasing peptide analogs (GA20-00546S)

) and neurodegeneration have a common etiopathogenesis involving subclinical inflammation and insulin that simultaneously affects obesity, T2DM and neurodegeneration in mouse and rat models of neurodegeneration development ...

Physiology (including cytology)

  • 2020 - 2022
    • •
  • 14 571 tis. Kč
    • •
  • 13 281 tis. Kč
    • •
  • GA ČR
Project

REM sleep behavior disorder predicting the risk of neurodegeneration (GA16-07879S)

of earliest phases of neurodegeneration. In addition to already established biomarkers to neurodegeneration....

FH - Neurologie, neurochirurgie, neurovědy

  • 2016 - 2020
    • •
  • 7 179 tis. Kč
    • •
  • 7 179 tis. Kč
    • •
  • GA ČR
Project

Multidisciplinary approach in the diagnosis of frontotemporal lobar degenerations and tauopathies new insights into pathogenetic mechanisms (NT12094)

the expression of specific selected proteins related to neurodegeneration. More precise pronounced neurodegeneration, will profoundly modify the accuracy of prognoses......

FH - Neurologie, neurochirurgie, neurovědy

  • 2011 - 2015
    • •
  • 10 440 tis. Kč
    • •
  • 10 440 tis. Kč
    • •
  • MZ
Project

Novel hybrid compounds in the cognitive decline caused by neurodegeneration (GA16-08554S)

results in amelioration of the cognitive decline associated with neurodegeneration...

FR - Farmakologie a lékárnická chemie

  • 2016 - 2018
    • •
  • 9 929 tis. Kč
    • •
  • 9 487 tis. Kč
    • •
  • GA ČR
Project

ADP-ribose metabolism and its role in neurological disease (GA22-00885S)

in DNA repair and ADP-ribose metabolism often trigger neurodegeneration or loss of the ADP-ribose hydrolase ARH3 triggers neurodegeneration. Finally, we shall......

Cell biology

  • 2022 - 2024
    • •
  • 11 766 tis. Kč
    • •
  • 11 766 tis. Kč
    • •
  • GA ČR
Project

The source of neurological pathology in PNKP-mutated disease (GN23-07330I)

Hereditary mutations in the DNA strand break repair protein polynucleotide kinase-phosphatase (PNKP) result in a spectrum of neuropathologies, ranging from mild neurodegeneration to severe neurodevelopmental dysfunction. PNKP is implicated i...

Genetics and heredity (medical genetics to be 3)

  • 2023 - 2025
    • •
  • 5 499 tis. Kč
    • •
  • 5 499 tis. Kč
    • •
  • GA ČR
Project

Advanced Glycomimetics for the Treatment of Age-Related Neurodegenerative Disorders A Complex Biological Exploration (GF25-15587K)

neurodegeneration. The Croatian-Czech project aims to comprehensively evaluate newly designed neurodegeneration and refine structural features for optimal pharmacologic performance and neurodegeneration in advanced biologi...

Pharmacology and pharmacy

  • 2025 - 2028
    • •
  • 12 860 tis. Kč
    • •
  • 12 860 tis. Kč
    • •
  • GA ČR
Project

The relationship between amyotrophic lateral sclerosis and the degree of cognitive impairment, markers of neurodegeneration and brain atrophy. A prospective study. (NR8491)

The aim of the study is to establish correlations between the the form of ALS (bulbar or limb onset), cognitive impairment and markers of neurodegeneration. The study is based on a complex initial evaluation of ALS patients (neuropsychologic...

FH - Neurologie, neurochirurgie, neurovědy

  • 2005 - 2008
    • •
  • 3 244 tis. Kč
    • •
  • 3 158 tis. Kč
    • •
  • MZ
Project

The role of neurodegeneration in pathogenesis, manifestations and prognosis of MTLE/HS - in vivo, ex vivo and in vitro perspective (NU22-04-00366)

of neurodegenerative pathways in epilepsy, mostly exploring neurodegeneration associated proteins with neurodegeneration at once on a large cohort of 300-350 patients suffering from temporal lobe......

Neurosciences (including psychophysiology)

  • 2022 - 2025
    • •
  • 10 693 tis. Kč
    • •
  • 10 693 tis. Kč
    • •
  • MZ
Project

IT4Neuro(degeneration) (EF18_069/0010054)

Goal of the pre-application research project is to establish system for production and evaluation of interdisciplinary research results with high potential for application of the results into therapy and diagnosis procedures based on IT technologies....

Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)

  • 2019 - 2023
    • •
  • 79 019 tis. Kč
    • •
  • 79 019 tis. Kč
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  • MŠMT
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