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221 (0,088s) •

Project

Quality of life in children with juvenile idiopathic arthritis Importance of allied health professions in the complex treatment programme (NT14149)

The project deals with the area of clinical contribution of allied health professionals to multidisciplinary care for paediatric patients with juvenile arthritis. Systematic expert work of the nurse specialist and therapists forms a...

FG - Pediatrie

  • 2013 - 2015
    • •
  • 1 789 tis. Kč
    • •
  • 1 789 tis. Kč
    • •
  • MZ
Project

Neutrophils in juvenile idiopathic arthritis biomarkers with potential to improve clinical treatment decisions and patient care (NU20-05-00320)

Juvenile idiopathic arthritis (JIA) is a multifactorial autoimmune disease with involvement of adaptive and also innate immunity. The biological therapy (IL-1ß, IL-6 and TNFa inhibitors) revolutionized patient care, but the...

Immunology

  • 2020 - 2023
    • •
  • 10 864 tis. Kč
    • •
  • 10 864 tis. Kč
    • •
  • MZ
Project

Ultrasonography of joints in children with juvenile idiopathic arthritis Assessment of subclinical synovitis and joint damage (NV16-33002A)

Hypothesis: The identification of subclinical synovitis and structural damage in the joints by musculoskeletal ultrasonography (MSUS) in children with juvenile idiopathic arthritis (JIA) will contribute to the monitoring an...

FG - Pediatrie

  • 2016 - 2021
    • •
  • 3 193 tis. Kč
    • •
  • 2 755 tis. Kč
    • •
  • MZ
Project

Relationship of intracellular methotrexate concentration to clinical and laboratory parameters of disease activity in children with idiopathic arthritis (NE6681)

Methotrexate is the most commonly used agent in the treatment of juvenile idiopathic artritis.In standard low-dose regimen it works in about 2/ of patients.Insufficient effect may be especially in children caused by its individual p...

FG - Pediatrie

  • 2001 - 2003
    • •
  • 1 727 tis. Kč
    • •
  • 1 697 tis. Kč
    • •
  • MZ
Project

Analysis of intracellular IL-1RA isoforms in patients with juvenile idiopathic arthritis and their relation to clinical features of the disease (NR7922)

Differentiation of production of IL-1RA izoforms in cell populations in peripheral blood/synovial tissue of JIA patients and peripheral blood of controls. Correlation of expression profile with clinical parameters and disease activity of JIA and IL-1...

FG - Pediatrie

  • 2004 - 2006
    • •
  • 5 022 tis. Kč
    • •
  • 4 826 tis. Kč
    • •
  • MZ
Project

Prognostic parameters in juvenile chronic arthritis (NE4879)

Evaluation of clinical,laboratory,genetic and imnulogic parameters from the point of view of diagnosis and prognosis of different forms of juvenile chronic arthritis.......

FP - Ostatní lékařské obory

  • 1998 - 2000
    • •
  • 3 460 tis. Kč
    • •
  • 2 768 tis. Kč
    • •
  • MZ
Project

Comparison of efficacy of cemented and non cemented and non cemented knee arthroplasty by patients with rheumatoid arthritis and juvenile rheumatoid arthritis. (IZ2916)

FJ - Chirurgie včetně transplantologie

  • 1995 - 1997
    • •
  • 1 540 tis. Kč
    • •
  • 1 540 tis. Kč
    • •
  • MZ
Project

Stress and idiopathic hyperprolactinaemia in patients with systemic lupus erythematosus, rheumatoid arthritis and autoimmune diabetes mellitus (NR8191)

diseases, mainly systemic lupus erythematosus (SLE). Idiopathic hyperprolactinaemia...

FE - Ostatní obory vnitřního lékařství

  • 2004 - 2006
    • •
  • 4 534 tis. Kč
    • •
  • 4 164 tis. Kč
    • •
  • MZ
Project

IL-35 a novel cytokine in systemic rheumatic diseases (NT12440)

IL-35 is a novel cytokine of IL-12 family with unknown functions in human diseases. Since our discovery of increased IL-35 in synovial fluid, its association with disease activity and potential pro-inflammatory role in rheumatoid arthritis (...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2011 - 2014
    • •
  • 7 701 tis. Kč
    • •
  • 7 701 tis. Kč
    • •
  • MZ
Project

Identification of biomarkers enabling risk estimation and therapy individualization in pediatric patients with juvenile and adolescent idiopathic scoliosis through analysis of temporal biochemical (NU21-08-00521)

with idiopathic scoliosis is still complex and individual for each patient. Non-coding RNAs and studying the molecular causes of idiopathic scoliosis. The present project focuses that are currently used to monitor bone metabolism i...

Biochemistry and molecular biology

  • 2021 - 2025
    • •
  • 15 180 tis. Kč
    • •
  • 15 115 tis. Kč
    • •
  • MZ
  • 1 - 10 out of 221