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Výsledek výzkumu

GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors

of SA to date. Multi-ancestry and admixture-specific meta-analyses were conducted within groups of significant African, East Asian, and European ancestry admixtures ancestry-matched controls. Analytical methods across mult...

Psychiatry

  • 2023
  • Jimp
  • Odkaz
Výsledek výzkumu

Method of phenotypic markers and biogeographic ancestry prediction namely for forensic purposes

The subject of this invention is prediction of externally visible characteristics and biogeographic ancestry of a person, namely for forensic purposes, by determination of genotypes in 9 SNP markers. Determination of phenotype characteristic...

EB - Genetika a molekulární biologie

  • 2013
  • O
Výsledek výzkumu

Testing the Reliability of Software Tools in Sex and Ancestry Estimation in a Multi-Ancestral Brazilian Sample

methods for estimation of ancestry much more complex, which confounds one of major requirements of ancestry assessment ? intra-population homogeneity. The present paper tests the accuracy of ancestry and sex assessment usi...

AC - Archeologie, antropologie, etnologie

  • 2014
  • Jx
  • Odkaz
Výsledek výzkumu

Application of multifactor dimensionality reduction analysis and Bayesian networks for eye color and ancestry prediction for forensic purposes in the Czech Republic

We present model based approach to create panel of SNP markers for eye color and ancestry prediction for application in the Czech Republic. The constructed network contained SNP markers rs1426654 and rs16891982 for ancestry determin...

EB - Genetika a molekulární biologie

  • 2013
  • Jx
  • Odkaz
Výsledek výzkumu

Polygenic risk modeling for prediction of epithelial ovarian cancer risk

of different ancestries: prospective data from 198,101 women of European ancestries; 7,669 women of East Asian ancestries; 1,072 women of African ancestries, and in 18,915 BRCA1 and 12,337 BRCA2 pathogenic variant...

Oncology

  • 2022
  • Jimp
  • Odkaz
Výsledek výzkumu

An International Adult Guideline for Making Clozapine Titration Safer by Using Six Ancestry-Based Personalized Dosing Titrations, CRP, and Clozapine Levels

worldwide by using ancestry-based dosing and titration. Adverse drug reaction (ADR for inpatients: 1) ancestry from Asia or the original people from the Americas with lower) ancestry from Asia or the original people from t...

Pharmacology and pharmacy

  • 2022
  • Jimp
  • Odkaz
Výsledek výzkumu

An international adult guideline for making clozapine titration safer by using six ancestry-based personalized dosing titrations, CRP, and clozapine levels

improving clozapine package inserts worldwide by using ancestry-based: 1) dosing and 2) elevations. People with ancestry from Asia (Pakistan to Japan) or the Americas’ original for inpatients: 1) Asian/Amerindian ancestry ...

Pharmacology and pharmacy

  • 2023
  • JSC
  • Odkaz
Výsledek výzkumu

Education and National Identity: Does the significance of Czech ancestry decline with higher education?

Individuals with higher education are less likely to emphasize the role of Czech ancestors for the national belonging. However, the emphasize of the Czech origin has been growing across all educational groups in recent years....

Sociology

  • 2018
  • C
Výsledek výzkumu

Lack of Population Diversity in Human Embryonic Stem-Cell Lines

We determined the genetic ancestry of large collection of stem-cell lines. We have found that widely distributed stem-cell lines lack population diversity and that none of these lines derive from populations with recent African ancestry<...

EB - Genetika a molekulární biologie

  • 2009
  • Jx
Výsledek výzkumu

A substantial prehistoric European ancestry amongst Ashkenazi maternal lineages

, have ancestry in prehistoric Europe, rather than the Near East or Caucasus. Furthermore, most of the remaining minor founders share a similar deep European ancestry......

EB - Genetika a molekulární biologie

  • 2013
  • Jx
  • Odkaz
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