Filtry
Pharmacokinetics of the cardioprotective drug dexrazoxane and its active metabolite ADR-925 with focus on cardiomyocytes and the heart
metabolite ADR-925. However, pharmacokinetic profile of both agents, particularly and disposition of DEX to ADR-925 in vitro (primary cardiomyocytes) and in vivo (rabbits cardiotoxicity. Our results show that DEX ...
Pharmacology and pharmacy
- 2018 •
- Jimp •
- Odkaz
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Clinically Translatable Prevention of Anthracycline Cardiotoxicity by Dexrazoxane Is Mediated by Topoisomerase II Beta and Not Metal Chelation
-chelating metabolite ADR-925. However, direct evidence is lacking, and recently proposed chelating metabolite ADR-925 (administered exogenously) was performed together: Intracellular concentrations of ADR...
Pharmacology and pharmacy
- 2021 •
- Jimp •
- Odkaz
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Development of LC-MS/MS method for the simultaneous analysis of the cardioprotective drug dexrazoxane and its metabolite ADR-925 in isolated cardiomyocytes and cell culture medium
simultaneous determination of the parent drug and its putative active metabolite ADR-925 the first LC-MS/MS method for simultaneous determination of DEX and ADR-925......
CB - Analytická chemie, separace
- 2013 •
- Jx •
- Odkaz
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
Synthesis and analysis of novel analogues of dexrazoxane and its open-ring hydrolysis product for protection against anthracycline cardiotoxicity in vitro and in vivo
chelating properties of its open ring metabolite, ADR-925, which may inhibit of dexrazoxane (MK-15, ES-5) and ADR-925 (KH-TA4, JR-159) were synthesized, and evaluated......
FR - Farmakologie a lékárnická chemie
- 2015 •
- Jx •
- Odkaz
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
ALTERNATIVE DISPUTE RESOLUTION
the pilot version of ADR (Alternative Dispute Resolution) and the version for 2016 of the ADR system, approaches to dispute resolution and media presentation of the ADR informations. The major difference is an extra form o...
Business and management
- 2017 •
- D
Rok uplatnění
D - Stať ve sborníku
Cross-border Alternative Dispute Resolutions
This paper focuses on the cross-border alternative dispute resolutins and the net of the European consumer centers. These centers help consumers with their disputes with sellers and works on the European Union, Iceland and Norway....
AE - Řízení, správa a administrativa
- 2010 •
- D
Rok uplatnění
D - Stať ve sborníku
Carriage of dangerous goods through road tunnels according to international agreement ADR
The article is informing of roads tunnels classification according to ADR, new duties and responsibilities leading from this activity.
JO - Pozemní dopravní systémy a zařízení
- 2009 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Analysis of the unsteady temperature field 925
The work deals with the analysis of the heat transfer in the investigated area of the project 925 for various geometries. The analysis of the temperature fields in time course are included....
Mechanical engineering
- 2019 •
- Vsouhrn
Rok uplatnění
Vsouhrn - Souhrnná výzkumná zpráva
Tangental Turning of Incoloy Alloy 925 Using Abrasive Water Jet
The paper deals with tangential turning of Incoloy alloy 925 with the diameter 50mm using the abrasive water jet. Experiment was done using the abrasive water jet of pressure p=400MPa and traverse speed at levels of v=1,5;3;4,5;6;7,5;9mm min...
JQ - Strojní zařízení a nástroje
- 2015 •
- D
Rok uplatnění
D - Stať ve sborníku
Alternative Resolution of Commercial Disputes
Basic themes of document: entrepreneurs; ombudsman; ADR; FIN-Net; SOLVIT...
AG - Právní vědy
- 2012 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
- 1 - 10 z 293