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114 (0,065s)

Výsledek výzkumu

RESEARCH LABORATORY - RELA

The paper covers a new way in managing marketing research using a research laboratory ReLa. ReLa system provides very effective data collection through an electronic questionnaire and an instant data transfer to the researches. The ...

AH - Ekonomie

  • 2007
  • D
Výsledek výzkumu

Nasazení informačního systému ReLa ve výuce předmětu Marketing II.

Information system ReLa (research laboratory) was used in the Marketing II. lectures. There are three views mentionedin the text on the integration of the system into the lectures -- lecturer, programmer and integrator....

AH - Ekonomie

  • 2007
  • D
Výsledek výzkumu

Subinhibitory Concentrations of Bacteriostatic Antibiotics Induce relA-Dependent and relA-Independent Tolerance to beta-Lactams

(p) ppGpp synthetase RelA is activated by deacylated tRNA in the ribosomal A-site, the antibiotic thiostrepton efficiently inhibits RelA activation by the A-site tRNA. The effect is independent of RelA functionality, speci...

Microbiology

  • 2017
  • Jimp
  • Odkaz
Výsledek výzkumu

Foodborne toxin Aflatoxin B 1 induced glomerular podocyte inflammation through proteolysis of RelA, downregulation of miR-9 and CXCR4/TXNIP/NLRP3 pathway

ubiquitindependent degradation of the transcription factor RelA through enhanced interaction of RelA with E3 ubiquitinligase tripartite motif containing 7 (TRIM7) in mouse podocyte clone-5 (MPC-5) and mouse glomeruli.Reduction of <...

Toxicology

  • 2024
  • Jimp
  • Odkaz
Výsledek výzkumu

Molecular mutagenesis of ppGpp: turning a RelA activator into an inhibitor

is an activator of the ribosome-associated ppGpp synthetase RelA, several ppGpp mimics have been developed as RelA inhibitors. However promising, the currently available ppGpp to identify a potent and specific inhibitor of RelA...

Biochemistry and molecular biology

  • 2017
  • Jimp
  • Odkaz
Výsledek výzkumu

A Method for Knowledge Representation to Design Intelligent Problems Solver in Mathematics Based on Rela-Ops Model

of knowledge, called the Rela-Ops model. This model includes foundation components of the Rela-Ops model is a class of objects which also have behaviors to solve problems on their own. The processing of algorithms for solving probl...

Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)

  • 2020
  • Jimp
  • Odkaz
Výsledek výzkumu

RelA-SpoT Homolog toxins pyrophosphorylate the CCA end of tRNA to inhibit protein synthesis

RelA-SpoT Homolog (RSH) enzymes control bacterial physiology through synthesis and degradation of the nucleotide alarmone (p)ppGpp. We recently discovered multiple families of small alarmone synthetase (SAS) RSH acting as toxins of toxin-ant...

Microbiology

  • 2021
  • Jimp
  • Odkaz
Výsledek výzkumu

Research Laboratory

Research Laboratory (abbr.ReLa) ReLa is a virtual laboratory, aimed at collection and evaluation of primary data acquired through inquiry systems. It is an interface supporting creative activity and intercommunication between scientific is a...

AE - Řízení, správa a administrativa

  • 2010
  • R
Výsledek výzkumu

Global interactome mapping reveals pro-tumorigenic interactions of NF-κB in breast cancer

cycle regulation and DNA replication. Central NF-κB transcription regulator RELA co by AlphaPulldown prediction. A complementary immunoprecipitation experiment recapitulates RELA of NF-κB activators to RELA. This study des...

Biochemistry and molecular biology

  • 2024
  • Jimp
  • Odkaz
Výsledek výzkumu

Knowledge-Based Model of Expert Systems Using Rela-Model

relations, called Rela-model, is presented in this paper. It has the components behavior to solve problems on it. The methods for solving problems based on Rela-model, effectiveness, have also been proved. Besides the solid mathema...

Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)

  • 2018
  • Jimp
  • Odkaz
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