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5 722 (0,173s) •

Project

The effect of tick saliva and salivary sialostatins on cellular stres responses and its implication to tick-borne enecephalitis virus transmission (GA19-15678S)

the analysis of stress responses including danger-triggered signaling, oxidative stress and endoplasmic reticulum stress responses. The analysis of cellular survival pathways encephalitis virus t...

Virology

  • 2019 - 2022
    • •
  • 6 516 tis. Kč
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  • 6 395 tis. Kč
    • •
  • GA ČR
Project

Regulation of translation during plant stress response (GA25-16195S)

In response to stress, protein synthesis comes to a halt and cells assemble a specialized active response to counteract the stress. This project aims to dissect that are required to maintain an active stress

Biochemistry and molecular biology

  • 2025 - 2027
    • •
  • 7 766 tis. Kč
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  • 7 766 tis. Kč
    • •
  • GA ČR
Project

Cellular responses to replication stress Mechanisms and the role of fragile sites in genomic instability (IAA501370902)

undermined by 'replication stress', possibly leading to DNA breakage and predisposition the functional links between replication stress, instability of genomic fragile sites and cell fate decisions, focusing on DNA damage respo...

EB - Genetika a molekulární biologie

  • 2009 - 2011
    • •
  • 3 242 tis. Kč
    • •
  • 3 242 tis. Kč
    • •
  • AV ČR
Project

Mechanisms of maintaining protein homeostasis in cancer. (GA22-17102S)

Stress response is a key feature of cancer cells that ensures enhanced protein stress. Heat shock factor-1 (HSF1) is a major stress-response transcription factor, the mechanisms leading to HSF1 activation ...

Cell biology

  • 2022 - 2024
    • •
  • 9 627 tis. Kč
    • •
  • 9 546 tis. Kč
    • •
  • GA ČR
Project

Elucidation of RACK1 role in translation regulation upon stress. (GJ19-07603Y)

. RACK1 is also a known component of stress granules (SGs). These ribonucleoprotein assemblies shape translation response upon stress conditions and possess cytoprotective in translation, stress response a...

Biochemistry and molecular biology

  • 2019 - 2022
    • •
  • 7 615 tis. Kč
    • •
  • 7 615 tis. Kč
    • •
  • GA ČR
Project

Unravelling novel intracellular trafficking regulators involved in plant stress response. (GJ20-20860Y)

indicate their role in cellular stress response. Characterization of those proteinsEndosomal trafficking is vital in plant development both in optimal and stress integrity preservation and therefore for plant resi...

Cell biology

  • 2020 - 2023
    • •
  • 6 368 tis. Kč
    • •
  • 6 368 tis. Kč
    • •
  • GA ČR
Project

Physiology of bat hibernation with respect to multistressor impacts (GA17-20286S)

plan to investigate variation of organismal and cellular responses to multiple and their factors of virulence and link pathogenic pressure and the cellular response cycle; 2) innate immune responses; 3) o...

GJ - Choroby a škůdci zvířat, veterinární medicina

  • 2017 - 2019
    • •
  • 15 361 tis. Kč
    • •
  • 15 316 tis. Kč
    • •
  • GA ČR
Project

Hormonal control of anti-stress reactions in insects (LH14047)

in antioxidative stress response. This involves the study of cellular metabolic pathways a conceptual basis for future hormonal regulation of stress responses in humans.) in the stimulation of anti-st...

ED - Fyziologie

  • 2014 - 2016
    • •
  • 1 950 tis. Kč
    • •
  • 1 950 tis. Kč
    • •
  • MŠMT
Project

Flotillin a novel player in plant stress signalling (GA14-09685S)

initiating protective cellular responses to establish stress tolerance. UnderstandingPlants respond to environmental stress such as drought, salinity and pathogen situations. Little is known, however, about the

CE - Biochemie

  • 2014 - 2018
    • •
  • 8 874 tis. Kč
    • •
  • 8 874 tis. Kč
    • •
  • GA ČR
Project

The role of PML in cellular senescence (IAA500390501)

for understanding cellular senescence and response to stress on the level of nuclear structurePML bodies are large dynamic nuclear complexes implicated in regulation of cellular senescence, however, their function...

EA - Morfologické obory a cytologie

  • 2005 - 2009
    • •
  • 3 474 tis. Kč
    • •
  • 3 474 tis. Kč
    • •
  • AV ČR
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