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1 601 (0,159s)

Project

Metabolomics 2.0 Comprehensive analytical methods and bioinformatics tools for the study of circadian rhythms (LTAUSA19124)

tools for the study of circadian rhythms. Recent improvements in chromatography (Metabolomics 2.0) for the study of circadian rhythms. Scientific publications with detailed activity between the Laboratory of Trans...

Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology

  • 2020 - 2022
  • 7 740 tis. Kč
  • 7 740 tis. Kč
  • MŠMT
Project

Role of internal time-keeping system in pathogenesis of colorectal cancer (GA13-08304S)

Epidemiologic studies demonstrated that disturbed circadian rhythms, often in mice. Specifically, (1) to establish whether rhythms of circadian clock and cell. We have discovered the presence of circadian ...

ED - Fyziologie

  • 2013 - 2017
  • 7 406 tis. Kč
  • 7 406 tis. Kč
  • GA ČR
Project

Circadian regulation of kynurenine pathway enzymes in rat brain and peripheral organs (GA23-07184S)

with the disruption of the kynurenine pathway. Our preliminary results show the circadian rhythms are required for energy metabolism. Their synthesis is regulated by several enzymes. The circadian system is a home...

Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology

  • 2023 - 2025
  • 7 392 tis. Kč
  • 7 392 tis. Kč
  • GA ČR
Project

Intracellular mechanisms of entrainment of circadian rhythm of vasopressin release from cultured suprachiasmatic neurons by VIP and melatonin. (ME 158)

Mammalian daily rhythms are driven by circadian pacemaker in suprachiasmatic maintain the circadian rhythmicity of vasopressin release for several weeks after on the rhythm and their intracellular mechanisms. We wi...

FH - Neurologie, neurochirurgie, neurovědy

  • 1998 - 2000
  • 1 124 tis. Kč
  • 679 tis. Kč
  • MŠMT
Project

The crosstalk between the endocannabinoid and circadian systems (GA17-14704S)

in this regard were so far unsuccessful. The circadian system (CDS) was linked to the etiology of metabolic diseases recently. The crosstalk between both systems is seldom the ECS in a circadian manner and examine its role...

ED - Fyziologie

  • 2017 - 2021
  • 4 884 tis. Kč
  • 4 695 tis. Kč
  • GA ČR
Project

Constrained analysis of reaction networks - a tool for experimental validation of models of biochemical and photobiological reactors (GA18-24397S)

observed metabolic/ultradian/circadian rhythms will be described as biochemical of kinetic parameters at which the model reproduces the observed oscillations/rhythms.......

Chemical engineering (plants, products)

  • 2018 - 2021
  • 8 101 tis. Kč
  • 7 240 tis. Kč
  • GA ČR
Project

Human circadian clock effect of annual season, daily schedule and genetics (IAA7011604)

of the underlying circadian pacemaker. Other circadian rhythms will be followed as wellFunctional state and resetting of the mammalian circadian clock are determined in darkness assigned to sleep and single bright...

ED - Fyziologie

  • 1996 - 1998
  • 2 352 tis. Kč
  • 821 tis. Kč
  • AV ČR
Project

Dynamics of complex reaction networks in enzyme reactors and photobioreactors (GA15-17367S)

in a photobioreactor. Experimentally observed metabolic/ultradian/circadian rhythms...

CI - Průmyslová chemie a chemické inženýrství

  • 2015 - 2018
  • 7 283 tis. Kč
  • 7 283 tis. Kč
  • GA ČR
Project

Determination of functional state of the human circadian system and its changes in depression and bipolar disorder (NT11474)

of physiological functions, so that many of them exhibit circadian rhythms. Failure circadian system and test its suitability to assess involvement of this system gene expression rhythms will be monitored in sampl...

ED - Fyziologie

  • 2010 - 2013
  • 3 400 tis. Kč
  • 3 400 tis. Kč
  • MZ
Project

Insight into the circadian system of the spontaneously hypertensive rat (SHR) during ontogenesis and in adulthood (GAP303/11/0668)

The mammalian circadian system exhibits a temporal control over physiological functions, including energy metabolism. Perturbation of the circadian organization may affect the energy metabolism and, vice versa, alt...

ED - Fyziologie

  • 2011 - 2013
  • 4 920 tis. Kč
  • 4 920 tis. Kč
  • GA ČR
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