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4 682 (0,146s) •

Project

Expression of papillomavirus antigenic epitopes in plants using plant viral vector (GA521/06/0973)

oncoprotein or L2 capsid protein.  We will focus on the expression of these heterologous proteins in plant host cells using PVX-based expression vector, namely pgR106. We expression and expression

EE - Mikrobiologie, virologie

  • 2006 - 2008
    • •
  • 3 909 tis. Kč
    • •
  • 3 909 tis. Kč
    • •
  • GA ČR
Project

Construction of the New Eukaryotic Expression System (1QS600220554)

, high-yield, inducible protein expression system capable of producing post by using non-pathogenic flagellate Leishmania tarentolae as a protein expression for the development of a tightly inducible protein

EB - Genetika a molekulární biologie

  • 2005 - 2008
    • •
  • 1 514 tis. Kč
    • •
  • 1 514 tis. Kč
    • •
  • AV ČR
Project

Detection of P-glycoprotein genes polymorphism as product of MDR1 gene (MDR1/Pgp) and MRP and expression of PgP, MRP1 and LRP on lymphocytes in patients with bronchial asthma, Croh´n disease (NR8954)

Expression of multiple drug resistance proteins and its polymorphism is likely. Determination of expression and polymorphism of these proteins can be one of significant optimal therapeutic strategy. The aim of the ...

FG - Pediatrie

  • 2006 - 2008
    • •
  • 2 764 tis. Kč
    • •
  • 2 549 tis. Kč
    • •
  • MZ
Project

*Development of cultivation and purification technologies for industrial production of recombinant vaccines. (FT-TA2/025)

*Research of possible expression of immunogenic proteins in the industrially proved microbial host cultures; formation of the expressed recombinant production strain and its culture characteristics. Optimization and automat...

EI - Biotechnologie a bionika

  • 2005 - 2008
    • •
  • 27 760 tis. Kč
    • •
  • 18 986 tis. Kč
    • •
  • MPO
Project

The expression of DMPK mRNA and DMPK protein in normal human tissues and the presence of nuclear foci containing (CUG)n and (CCUG)n expanded transcripts of DMPK in tissues of patients with myotonic (NS9877)

repeat expression in the development of DM pathology, we plan (1) to establish the identity of normal tissues and cell types in which the DMPK protein and the DMPK mRNA are expressed, and, (2) to identify foci containing C...

FH - Neurologie, neurochirurgie, neurovědy

  • 2008 - 2011
    • •
  • 1 962 tis. Kč
    • •
  • 1 962 tis. Kč
    • •
  • MZ
Project

The role of proteins BIR-1/Survivin in regulation of development and gene expression (GA304/07/0529)

The protein Survivin is expressed in most human cancers while its expression and development. This adds a new function to a protein involved in the regulation of apoptosis. elegans development and search for new in...

EA - Morfologické obory a cytologie

  • 2007 - 2009
    • •
  • 4 926 tis. Kč
    • •
  • 4 926 tis. Kč
    • •
  • GA ČR
Project

Expression of genes and proteins playing a role in the human reproduction - damage biomarkers (NS10009)

the relationship between gene expression in testes and sperm and seminal plasma proteins entity - the dysgenesis syndrome. To examine the expression level of acrosome the differences in localization of sperm, cytoskeletal ...

EB - Genetika a molekulární biologie

  • 2008 - 2011
    • •
  • 3 005 tis. Kč
    • •
  • 3 005 tis. Kč
    • •
  • MZ
Project

Gene expression and posttranslational modification during germination of aerial spores of streptomycetes (GA203/02/1421)

to examine expression and posttranslational modification of proteins before and after the first DNA replication. Quantitative changes in gene expression will be examined using 15N-incorporation and tryptic peptides of mode...

EB - Genetika a molekulární biologie

  • 2002 - 2004
    • •
  • 3 109 tis. Kč
    • •
  • 1 573 tis. Kč
    • •
  • GA ČR
Project

Biosimilars building of knowledge base for production of therapeutic proteins using heterologous expression systems. (2A-2TP1/030)

Proteins produced in heterologous expression systems, are the fastest growing segment in pharmaceutical industry. The approaching termination of validity of several and detailed utilisation of individual expression systems,...

EI - Biotechnologie a bionika

  • 2007 - 2011
    • •
  • 23 738 tis. Kč
    • •
  • 17 666 tis. Kč
    • •
  • MPO
Project

The effect of mutations and morphogenetic differences in matrix proteins on assembly and transport of retroviral capsids (GA203/98/P151)

Matrix protein (MA) of Mason-Pfizer monkey virus (M-PMV), which will be cloned into bacterial expression vector. The conditions for expression of this mutant of metabolically labeled protein will be prepared for NM...

CE - Biochemie

  • 1998 - 2000
    • •
  • 822 tis. Kč
    • •
  • 703 tis. Kč
    • •
  • GA ČR
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