In vivo 31P MR spectroscopy of human kidney grafts using the 2D-chemical shift imaging method
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F11%3A00002463" target="_blank" >RIV/00023001:_____/11:00002463 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.transproceed.2010.11.027" target="_blank" >http://dx.doi.org/10.1016/j.transproceed.2010.11.027</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.transproceed.2010.11.027" target="_blank" >10.1016/j.transproceed.2010.11.027</a>
Alternative languages
Result language
angličtina
Original language name
In vivo 31P MR spectroscopy of human kidney grafts using the 2D-chemical shift imaging method
Original language description
The aim of this work was to evaluate the possibility to use in vivo (31)P magnetic resonance spectroscopy (MRS) for the diagnosis of kidney graft dysfunction after transplantation. We examined 68 kidney grafted patients using a 1.5 T MR scanner. (31)P MRS was performed using the 2D-chemical shift imaging method. The patients were divided into 4 groups: acute rejection episode; acute tubular necrosis; late graft dysfunction; or good renal function. We measured the signal intensities of phosphomonoesters(PME), inorganic phosphate (Pi), phosphodiesters (PDE), and ?-, ?-, ?-adenosine triphosphate (ATP; with contributions of ?- and ?-adenosine diphosphate) and their ratios. Patients with an acute rejection episodes showed a significantly elevated PME/?-ATPand PDE/?-ATP, PME/Pi, and PDE/Pi signal ratios compared with the control group. The group with acute tubular necrosis had decreased ratios. Patients with late graft dysfunction revealed only an insignificant decrease in PME/Pi and PDE/P
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FS - Medical facilities, apparatus and equipment
OECD FORD branch
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Result continuities
Project
<a href="/en/project/NT11275" target="_blank" >NT11275: Phosphorus MR spectroscopy in vivo at 3T</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Transplantation Proceedings
ISSN
0041-1345
e-ISSN
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Volume of the periodical
43
Issue of the periodical within the volume
5
Country of publishing house
US - UNITED STATES
Number of pages
6
Pages from-to
1570-1575
UT code for WoS article
000292279800033
EID of the result in the Scopus database
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