The association between APOA5 haplotypes and plasma lipids is not modified by energy or fat intake: The Czech HAPIEE study
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F14%3A00058919" target="_blank" >RIV/00023001:_____/14:00058919 - isvavai.cz</a>
Alternative codes found
RIV/75010330:_____/14:00010719
Result on the web
<a href="http://www.sciencedirect.com/science/article/pii/S0939475313001993" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0939475313001993</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.numecd.2013.08.008" target="_blank" >10.1016/j.numecd.2013.08.008</a>
Alternative languages
Result language
angličtina
Original language name
The association between APOA5 haplotypes and plasma lipids is not modified by energy or fat intake: The Czech HAPIEE study
Original language description
Background and aims: Several smaller studies reported interactions between dietary factors and apolipoprotein A5 (APOA5) gene polymorphisms in determination of plasma lipids. We tested interactions between APOA5 haplotypes and dietary intake in determination of plasma triglycerides (TG) and other lipids. Methods and results: Participants (5487 males and females aged 45-69) were classified according to the number (0, 1, 2+) of minor APOA5 alleles (using T-1131 > C; rs662799 and Ser19 > Trp; rs3135506 polymorphisms) and into three groups of low (bottom 25%), medium (26the-75th percentile) and high (top 25%) of intake of total energy and total, saturated and polyunsaturated fats, assessed by food frequency questionnaire. The age-sex adjusted geometric means of plasma TG increased with the number of minor alleles, from 1.57 (standard error 0.01), to 1.79 (0.02) to 2.29 (0.10) mmol/L (p < 0.00001) but TG did not differ between groups with low, medium and high total energy intake (p = 0.251)
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Nutrition, metabolism, and cardiovascular diseases
ISSN
0939-4753
e-ISSN
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Volume of the periodical
24
Issue of the periodical within the volume
3
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
5
Pages from-to
243-247
UT code for WoS article
000333039300009
EID of the result in the Scopus database
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