Accuracy of colon capsule endoscopy for colorectal neoplasia detection in individuals referred for a screening colonoscopy
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F19%3A00078367" target="_blank" >RIV/00023001:_____/19:00078367 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/19:10396706 RIV/00179906:_____/19:10396706 RIV/00216224:14110/19:00108525 RIV/00216208:11150/19:10396706 and 2 more
Result on the web
<a href="http://downloads.hindawi.com/journals/grp/2019/5975438.pdf" target="_blank" >http://downloads.hindawi.com/journals/grp/2019/5975438.pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1155/2019/5975438" target="_blank" >10.1155/2019/5975438</a>
Alternative languages
Result language
angličtina
Original language name
Accuracy of colon capsule endoscopy for colorectal neoplasia detection in individuals referred for a screening colonoscopy
Original language description
Backround. Capsule colonoscopy might present an alternative to colonoscopy for colorectal neoplasia screening. Aim. To assess the accuracy of second-generation capsule colonoscopy (CCE2) for colorectal neoplasia detection compared with conventional colonoscopy (CC). Methods. From 2011-2015, we performed a multicenter, prospective, cross-over study evaluating the use of CCE2 as a possible colorectal cancer (CRC) screening test based on the assessment of the method's characteristics (accuracy) and safety and patient acceptance of the routine. Enrolled participants fulfilled the CRC screening population criteria if they were asymptomatic, were older than 50, and had no personal or familial history of colorectal neoplasia. The primary outcome was accuracy for the detection of polyps >= 6 mm. Secondary outcomes were accuracy for all polyps, polyps >= 10 mm, adenomas >= 10 mm, and cancers, the quality of bowel cleansing, safety, and CCE2 acceptability by the screening population. Results. A total of 236 individuals were examined; 11 patients (5%) were excluded. Therefore, 225 subjects (95%) were considered in the intention-to-screen (ITS) group. A total of 201 patients (89%) completed both examinations successfully (per protocol group). In the ITS group, polyps were diagnosed during CC in 114 subjects (51%); polyps >= 6 mm, polyps >= 10 mm, and adenomas >= 10 mm were diagnosed in 34 (15%), 16 (7%), and 11 (5%) patients, respectively. The sensitivity of CCE2 for polyps >= 6 mm, polyps >= 10 mm, and adenomas >= 10 mm was 79% (95% confidence interval (CI): 62-91%), 88% (95% CI: 62-98%), and 100% (95% CI: 72-100%), respectively. Conclusion. Second-generation capsule colonoscopy is a safe, noninvasive, and sensitive method for colorectal neoplasia detection although CC remains the preferred method for considerable proportion of subjects. CCE2 may therefore be accepted as the primary screening test for colorectal cancer screening.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30219 - Gastroenterology and hepatology
Result continuities
Project
<a href="/en/project/NV16-29614A" target="_blank" >NV16-29614A: The comparison of the efficiency of colon capsule endoscopy and optical colonoscopy in patients with positive immunochemical fecal occult blood test</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Gastroenterology research and practice [online]
ISSN
1687-6121
e-ISSN
—
Volume of the periodical
2019
Issue of the periodical within the volume
September 3
Country of publishing house
GB - UNITED KINGDOM
Number of pages
8
Pages from-to
"art. no. 5975438"
UT code for WoS article
000486404300001
EID of the result in the Scopus database
2-s2.0-85072396755