Genetics of cardiovascular disease: How far are we from personalized CVD risk prediction and management?
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F21%3A00081014" target="_blank" >RIV/00023001:_____/21:00081014 - isvavai.cz</a>
Result on the web
<a href="https://www.mdpi.com/1422-0067/22/8/4182" target="_blank" >https://www.mdpi.com/1422-0067/22/8/4182</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/ijms22084182" target="_blank" >10.3390/ijms22084182</a>
Alternative languages
Result language
angličtina
Original language name
Genetics of cardiovascular disease: How far are we from personalized CVD risk prediction and management?
Original language description
Despite the rapid progress in diagnosis and treatment of cardiovascular disease (CVD), this disease remains a major cause of mortality and morbidity. Recent progress over the last two decades in the field of molecular genetics, especially with new tools such as genome-wide association studies, has helped to identify new genes and their variants, which can be used for calculations of risk, prediction of treatment efficacy, or detection of subjects prone to drug side effects. Although the use of genetic risk scores further improves CVD prediction, the significance is not unambiguous, and some subjects at risk remain undetected. Further research directions should focus on the "second level" of genetic information, namely, regulatory molecules (miRNAs) and epigenetic changes, predominantly DNA methylation and gene-environment interactions.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30201 - Cardiac and Cardiovascular systems
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
International journal of molecular sciences
ISSN
1661-6596
e-ISSN
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Volume of the periodical
22
Issue of the periodical within the volume
8
Country of publishing house
CH - SWITZERLAND
Number of pages
19
Pages from-to
"art. no. 4182"
UT code for WoS article
000644350900001
EID of the result in the Scopus database
2-s2.0-85104327517