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Head-to-head comparison of T1 mapping and electroanatomical voltage mapping in patients with ventricular arrhythmias

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F23%3A00084231" target="_blank" >RIV/00023001:_____/23:00084231 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11110/23:10469069

  • Result on the web

    <a href="https://www.sciencedirect.com/science/article/pii/S2405500X22009525?via%3Dihub#coi0010" target="_blank" >https://www.sciencedirect.com/science/article/pii/S2405500X22009525?via%3Dihub#coi0010</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.jacep.2022.10.035" target="_blank" >10.1016/j.jacep.2022.10.035</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Head-to-head comparison of T1 mapping and electroanatomical voltage mapping in patients with ventricular arrhythmias

  • Original language description

    BACKGROUND Electroanatomical voltage mapping (EAVM) has been compared with late gadolinium enhancement cardiovascular magnetic resonance (LGE-CMR), which cannot delineate diffuse fibrosis. T1-mapping CMR overcomes the limitations of LGE-CMR, but it has not been directly compared against EAVM. OBJECTIVES This study aims to assess the relationship between left ventricular (LV) endocardial voltage obtained by EAVM and extracellular volume (ECV) obtained by T1 mapping. METHODS The study investigated patients who underwent endocardial EAVM for ventricular arrhythmias (CARTO 3, Biosense Webster) together with preprocedural contrast-enhanced T1 mapping (Ingenia 3T, Philips Healthcare). After image integration, EAVM datapoints were projected onto LGE-CMR and ECV-encoded images. Average values of unipolar voltage (UV), bipolar voltage (BV), LGE transmurality, and ECV were merged from corresponding cardiac segments (6 per slice) and pooled for analysis. RESULTS The analysis included data from 628 segments from 18 patients (57 +/- 13 years of age, 17% females, LV ejection fraction 48% +/- 14%, nonischemic/ischemic cardiomyopathy/controls: 8/6/4 patients). Based on the 95th and 5th percentile values obtained from the controls, ECV &gt;33%, BV &lt;2.9 mV, and UV &lt;6.7 mV were considered abnormal. There was a significant inverse association between voltage and ECV, but only in segments with abnormal ECV. Increased ECV could predict abnormal BV and UV with acceptable accuracy (area under the curve of 0.78 [95% CI: 0.74-0.83] and 0.84 [95% CI: 0.79-0.88]). CONCLUSIONS This study found a significant inverse relationship between LV endocardial voltage and ECV. Real-time integration of T1 mapping may guide catheter mapping and may allow identification of areas of diffuse fibrosis potentially related to ventricular arrhythmias. (J Am Coll Cardiol EP 2023;9:740-748) (c) 2023 Published by Elsevier on behalf of the American College of Cardiology Foundation.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30201 - Cardiac and Cardiovascular systems

Result continuities

  • Project

  • Continuities

    N - Vyzkumna aktivita podporovana z neverejnych zdroju

Others

  • Publication year

    2023

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    JACC Clinical Electrophysiology

  • ISSN

    2405-500X

  • e-ISSN

    2405-5018

  • Volume of the periodical

    9

  • Issue of the periodical within the volume

    6

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    9

  • Pages from-to

    740-748

  • UT code for WoS article

    001059899300001

  • EID of the result in the Scopus database

    2-s2.0-85160747153