Acute effect of atrial fibrillation on circulating natriuretic peptides: the influence of heart rate, rhythm irregularity, and left atrial pressure overload

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F23%3A00084417" target="_blank" >RIV/00023001:_____/23:00084417 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11110/23:10470987

Result on the web

<a href="https://www.sciencedirect.com/science/article/pii/S0002914923010585?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0002914923010585?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.amjcard.2023.09.060" target="_blank" >10.1016/j.amjcard.2023.09.060</a>

Result language

angličtina

Original language name

Acute effect of atrial fibrillation on circulating natriuretic peptides: the influence of heart rate, rhythm irregularity, and left atrial pressure overload

Original language description

Plasma natriuretic peptides (NPs) are increased in patients with atrial fibrillation (AF) compared with the patients with sinus rhythm. This study investigated whether this phenomenon is intrinsic to heart rhythm irregularity and independent of the heart rate and left atrial pressure (LAP) overload. We investigated 46 patients (age: 59 &lt;/n&gt; 10 years, male gender: 77%) with non-valvular paroxysmal AF who were scheduled for catheter ablation and had documented stable sinus rhythm for at least 18 hours before the procedure. All patients underwent direct measurement of right atrial pressure and LAP, simultaneously with assessment of plasma B-type NP, N-terminal pro-brain NP, and mid-regional pro atrial NP. The baseline measurement was followed by induction of AF by rapid atrial pacing in the first 24 patients and by regular pacing from the coronary sinus at 100/min (corresponding to the mean heart rate during induced AF) in the latter 22 patients. Hemodynamic assessment and blood sampling were repeated after 20 min of the ongoing AF or fast regular paging. The baseline characteristics and hemodynamic measurements were comparable between study groups; however, patients in the regular atrial pacing group had a higher body mass index and a larger left atrial diameter compared with the induced AF group. Plasma levels of all 3 NPs increased significantly during induced AF but not during fast regular pacing, and the increase of NPs was independent of right atrial pressure and LAP. Baseline concentrations of NPs and heart rhythm irregularity were the only independent predictors of increased NPs.(c) 2023 Elsevier Inc. All rights reserved.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30201 - Cardiac and Cardiovascular systems

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

American journal of cardiology

ISSN

0002-9149

e-ISSN

1879-1913

Volume of the periodical

208

Issue of the periodical within the volume

December 1

Country of publishing house

US - UNITED STATES

Number of pages

8

Pages from-to

156-163

UT code for WoS article

001092219100001

EID of the result in the Scopus database

2-s2.0-85173656416