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Growth-inhibiting activity of transcription factor C/EBPalpha, its role in haematopoiesis and its tumour suppressor or oncogenic properties in leukaemias

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023736%3A_____%2F07%3A00007131" target="_blank" >RIV/00023736:_____/07:00007131 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Growth-inhibiting activity of transcription factor C/EBPalpha, its role in haematopoiesis and its tumour suppressor or oncogenic properties in leukaemias

  • Original language description

    The CCAAT/enhancer binding protein alpha (C/EBPalpha) is a member of a family of leucine zipper transcription factors and plays important roles in myeloid differentiation. Learning more about the precise molecular functions of this transcription factor and how these are affected by leukemogenic mutations should lead to an improved understanding of the cellular functions that are disrupted in patients with acute myeloid leukemia (AML)

  • Czech name

    Aktivita transkripčního faktoru C/EBPalpha inhibující růst buněk, jeho úloha v hematopoeze a jeho nádor potlačující a naopak onkogenní vlastnosti u leukémií

  • Czech description

    CCAAT/enhancer binding protein alpha (C/EBPalpha) je členem rodiny transkripčních faktorů obsahujících leucinový zip a hraje důležitou úlohy v diferenciaci myeloidních buněk. Detailnější studium tohoto transkripčního faktoru a jak je ovlivněn mutacemi zahrnutými v leukogeneze by měla usnadnit pochopení jak jsou jeho buněčné funkce porušeny u pacientů s akutní myeloidní leukémií (AML)

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FD - Oncology and haematology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/NR9045" target="_blank" >NR9045: The role of RUNX1, EVI1 and CEBPA genes in the pathogenesis of leukemias and pre-leukemias</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2007

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Folia Biologica

  • ISSN

    0015-5500

  • e-ISSN

  • Volume of the periodical

    53

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    12

  • Pages from-to

    97-108

  • UT code for WoS article

  • EID of the result in the Scopus database