Inhibition of TGF-beta signaling for the treatment of tumor metastasis and fibrotic diseases

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023736%3A_____%2F11%3A00009325" target="_blank" >RIV/00023736:_____/11:00009325 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.2174/157436211794109398" target="_blank" >http://dx.doi.org/10.2174/157436211794109398</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2174/157436211794109398" target="_blank" >10.2174/157436211794109398</a>

Result language
angličtina
Original language name
Inhibition of TGF-beta signaling for the treatment of tumor metastasis and fibrotic diseases
Original language description
Transforming growth factor-beta is a cytokine involved in cell proliferation, apoptosis, differentiation, angiogenesis, cell adhesion, migration, extracellular matrix deposition, wound healing and immune response. TGF-beta supresses tumor growth in earlyphase of neoplasia, while promotes tumor progression and metastasis in later phases.Therefore, several possibilities for the disruption of TGF-beta signaling is very important in the treatment of tumor metastasis and fibrotic diseases.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Project
<a href="/en/project/LC06044" target="_blank" >LC06044: Center for Experimental Hematology</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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